B1390
比沙可啶
analytical standard, for drug analysis
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关于此项目
经验公式（希尔记法）:
C22H19NO4
化学文摘社编号:
分子量:
361.39
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
210-044-4
MDL number:
InChI key
KHOITXIGCFIULA-UHFFFAOYSA-N
InChI
1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
SMILES string
CC(=O)Oc1ccc(cc1)C(c2ccc(OC(C)=O)cc2)c3ccccn3
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
Quality Level
Gene Information
human ... CHRM4(1132)
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Bisacodyl is a diphenylmethane derivative, mainly used as a stimulant laxative for treating constipation.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Michael A Kamm et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 9(7), 577-583 (2011-03-29)
Although stimulant laxatives have been used for many years to treat patients with constipation, their clinical value has been questioned, and there have been few high-quality trials to assess their efficacy. We tested the efficacy and safety of 4 weeks
V Giorgio et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 25(1), 70-78 (2012-10-04)
Severe pediatric slow transit constipation (STC) is commonly due to intrinsic colonic neuromuscular disease. We sought to correlate neuromuscular histological phenotypes in pediatric STC with colonic manometric phenotypes using high-resolution manometry (HRM). We tested the hypothesis that failure of motor
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk (2011)
Mercedes Ibáñez et al.
Diseases of the colon and rectum, 54(12), 1578-1584 (2011-11-10)
No consensus exists regarding the optimal bowel preparation regimen for patients with poor bowel cleansing at a previous colonoscopy. We investigated the usefulness of an intensive cleansing regimen for repeat colonoscopy after previous failure of bowel preparation. A prospective observational
Christian Friedrich et al.
Drug metabolism and pharmacokinetics, 26(5), 458-464 (2011-06-24)
The aim of this study was to determine whether administration of the prodrugs bisacodyl (Bisa) and sodium picosulfate (SPS) leads to excretion of their common active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), in breast milk. Two groups of 8 healthy lactating women who
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