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Merck
CN

A138

Sigma-Aldrich

Aminobenztropine

solid

别名:

ABT

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About This Item

经验公式(希尔记法):
C21H26N2O
CAS号:
分子量:
322.44
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

表单

solid

质量水平

颜色

white

溶解性

0.1 M HCl: soluble
0.1 M NaOH: insoluble
DMSO: soluble
methanol: soluble

SMILES字符串

CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4N

InChI

1S/C21H26N2O/c1-23-16-11-12-17(23)14-18(13-16)24-21(15-7-3-2-4-8-15)19-9-5-6-10-20(19)22/h2-10,16-18,21H,11-14,22H2,1H3

InChI key

KZFDKINRISJFCO-UHFFFAOYSA-N

生化/生理作用

High affinity muscarinic ligand that has been used for affinity purification of muscarinic cholinergic receptors.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Haga et al.
The Journal of biological chemistry, 258(22), 13575-13579 (1983-11-25)
A novel compound, 3-(2'-aminobenzhydryloxy)-tropane (ABT), and an ABT-agarose gel were synthesized and used for the purification of solubilized muscarinic receptors. ABT had a high affinity with an apparent dissociation constant (Kd) of 7 nM for the muscarinic receptors solubilized from
Takafumi Tomida et al.
The Journal of toxicological sciences, 42(5), 641-650 (2017-09-15)
The utility of HepaRG cells as an in vitro cell-based assay system for predicting drug-induced phospholipidosis (PLD) was investigated. In experiment 1, 10 PLD-positive compounds and 11 PLD-negative compounds were selected. HepaRG cells were treated with each compound for 48
Ryuji Kato et al.
Drug metabolism and disposition: the biological fate of chemicals, 47(10), 1093-1096 (2019-07-22)
Although the pathophysiology of carbamazepine-induced idiosyncratic or hypersensitivity reactions is unclear, they are presumed to be immune mediated, involving a complex interaction between drug metabolism and activation of the immune system. Cell stress can be caused by reactive metabolites, and
Teja Klancic et al.
Biomedicines, 9(1) (2021-01-16)
Pulsed antibiotic treatment (PAT) early in life increases risk of obesity. Prebiotics can reduce fat mass and improve metabolic health. We examined if co-administering prebiotic with PAT reduces obesity risk in rat pups weaned onto a high fat/sucrose diet. Pups
Zhongyu Chiam et al.
The Science of the total environment, 688, 398-408 (2019-06-28)
Elevated levels of airborne particulate matter (PM) pose health risks to populations living in many cities worldwide. To remediate the impact of air pollution, urban greening has been increasingly explored as a possible way to remove PM from the surroundings.

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