Anti-CD68 antibody, Rabbit monoclonal

CD68 is an intracellular glycoprotein mainly expressed on macrophages and monocytes. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is also expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) (M1-M5 types), and granulocytic sarcoma.
CD68 (cluster of differentiation 68) gene is mapped to human chromosome 17p13.1. The gene codes for a glycoprotein, macrosialin. The encoded protein belongs to the family of LAMP (lysosome-associated membrane glycoproteins) proteins. Macrosialin contains a glycosylated mucin-like domain.

Synthetic peptide derived from the internal region of the human CD68 protein.

Monoclonal Anti-CD68 antibody from rabbit has been used for immunohistochemistry.

CD68 (cluster of differentiation 68), a scavenger receptor, significantly participates in the development of Alzheimer′s disease. CD68 serves as a prognostic marker in tumor cells. Deletion of the gene is known to cause reduction in the bone resorption capacity.

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0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

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