推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 83 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
proteolytically cleaved (Val1697)
基因信息
human ... NOTCH2(4853)
一般描述
抗-NOTCH2(Cleaved-Val1697)抗体可检测激活的NOTCH2(Cleaved-Val1697)蛋白。
免疫原
针对人源 NOTCH2 的合成肽产生抗血清。
免疫原范围：1678-1727
免疫原范围：1678-1727
生化/生理作用
现已确知NOTCH2基因参与癌症细胞的增殖、细胞周期进展和集落形成。在肝细胞癌和唾液腺腺样囊性癌中观察到该基因上调。NOTCH2 的敲除增加了癌细胞对化疗药物（如5-氟脲嘧啶）的敏感性。NOTCH2在肝脏发育的调节中起重要作用。
特点和优势
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果，我们将给予您完全的赔偿或更换抗体。 了解更多。
外形
兔IgG，溶于磷酸盐缓冲盐水（不含Mg2+和Ca2+），pH7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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