SAB4501074
Anti-GAD67 Antibody
rabbit polyclonal
别名:
67 kDa glutamic acid decarboxylase, GAD-67, GAD1, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
mouse, human, rat
Citations:
3
Technique(s):
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
产品名称
Anti-GAD1 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 66 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GAD1(2571)
Biochem/physiol Actions
GAD1 gene (glutamate decarboxylase 1) participates in GABA (γ-aminobutyric acid) synthesis. Variations in GAD1 results in hyperactivity in attention-deficit/hyperactivity disorder. It is also characterized with childhood-onset schizophrenia and cortical gray matter volume loss.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Anti-GAD1 antibody detects endogenous levels of total GAD1 protein.
GAD1 gene (glutamate decarboxylase 1) codes for a glutamic acid decarboxylase enzyme (GAD67), that is of 67 kDa. It is mapped to human chromosome 2q31.1.
Immunogen
The antiserum was produced against synthesized peptide derived from human GAD1.
Immunogen Range: 471-520
Immunogen Range: 471-520
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
GAD1 Gene Expression in Blood of Patients with First-Episode Psychosis
Yee JY, et al.
PLoS ONE, 12(1), e0170805-e0170805 (2017)
GAD1 gene polymorphisms are associated with hyperactivity in Attention-Deficit/Hyperactivity Disorder
Bruxel EM, et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 171(8), 1099-1104 (2016)
GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss.
Addington AM, et al.
Molecular Psychiatry, 10(6), 581-588 (2005)
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