Anti-GAD1 antibody produced in rabbit

Anti-GAD1 antibody detects endogenous levels of total GAD1 protein.

GAD1 gene (glutamate decarboxylase 1) codes for a glutamic acid decarboxylase enzyme (GAD67), that is of 67 kDa. It is mapped to human chromosome 2q31.1.

The antiserum was produced against synthesized peptide derived from human GAD1.

Immunogen Range: 471-520

GAD1 gene (glutamate decarboxylase 1) participates in GABA (γ-aminobutyric acid) synthesis. Variations in GAD1 results in hyperactivity in attention-deficit/hyperactivity disorder. It is also characterized with childhood-onset schizophrenia and cortical gray matter volume loss.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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