GAD1
glutamate decarboxylase 1 (brain, 67kDa)
别名:
CPSQ1, GAD, SCP
物种:
Human GAD1 (2571), Mouse Gad1 (14415), Rat Gad1 (24379), sheep GAD1 (101117393), domestic cat GAD1 (493699), domestic guinea pig Gad1 (100271904), naked mole-rat Gad1 (101725846), cow GAD1 (517552), fruit fly Gad1 (38484), chicken GAD1 (395743)
UniProtKB ID:
基因ID:
- Human(2571) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
- Mouse(14415) glutamate decarboxylase 1
- Rat(24379) glutamate decarboxylase 1
- sheep(101117393) glutamate decarboxylase 1 (brain, 67kDa)
- domestic cat(493699) glutamate decarboxylase 1 (brain, 67kDa)
- domestic guinea pig(100271904) glutamate decarboxylase 1
- naked mole-rat(101725846) glutamate decarboxylase 1 (brain, 67kDa)
- cow(517552) glutamate decarboxylase 1 (brain, 67kDa)
- fruit fly(38484) Glutamic acid decarboxylase 1
- chicken(395743) glutamate decarboxylase 1 (brain, 67kDa)
- dog(478794) glutamate decarboxylase 1 (brain, 67kDa)
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ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
抗GAD67抗体，克隆1G10.2, clone 1G10.2, Chemicon®, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-GAD67 Antibody, clone 1G10.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-GAD67抗体，克隆1G10.2，生物素结合物, clone 1G10.2, from mouse, biotin conjugate,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry
immunohistochemistry
Anti-GAD1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
抗-GAD1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot