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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 44 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ADORA2A(135)
一般描述
Anti-ADORA2A Antibody detects endogenous levels of total ADORA2A protein.
Adenosinergic A2A receptor (ADORA2A) is a G-protein-coupled receptor and is expressed in the brain. It is located on human chromosome 22q11.23.
免疫原
The antiserum was produced against synthesized peptide derived from human ADORA2A.
Immunogen Range: 120-169
Immunogen Range: 120-169
生化/生理作用
Activation of the adenosine A2a receptor (ADORA2A) prevents T-cell proliferation and production of pro-inflammatory cytokines. Mutations in adenosinergic A2A receptor (ADORA2A) controls the psychomotor vigilance and the effects of caffeine in NREM (non-rapid-eye movement) sleep.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation
Bodenmann S, et al.
British Journal of Pharmacology, 165(6), 1904-1913 (2012)
Adenosine A(2A) receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder.
Freitag CM
European Child & Adolescent Psychiatry, 19(1), 67-74 (2010)
A genetic variation in the ADORA2A gene modifies age at onset in Huntington's disease
Dhaenens CM, et al.
Neurobiology of Disease, 35(3), 474-476 (2009)
[Adenosine A2A receptor as a drug target for treatment of sepsis]
Sivak KV, et al.
Molekuliarnaia Biologiia, 50(2), 231-245 (2016)
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