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SAB4300125

Sigma-Aldrich

Anti-phospho-NFKBIA (pSer32/pSer36) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-IKBA antibody produced in rabbit, Anti-MAD-3 antibody produced in rabbit, Anti-NFKBI antibody produced in rabbit, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha antibody produced in rabbit

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100 μL
¥5,169.41
0.2 ML
¥9,425.34
0.5 ML
¥17,956.83

¥5,169.41

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100 μL
¥5,169.41
0.2 ML
¥9,425.34
0.5 ML
¥17,956.83

About This Item

MDL编号:
MFCD01633603
UNSPSC代码:
12352203
NACRES:
NA.41

¥5,169.41

有货详情

生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

~39 kDa

种属反应性

human, mouse

浓度

1 mg/mL

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此商品
516589445401245607
异氰酸环己甲酯 97%

571997

异氰酸环己甲酯

环戊基异氰酸酯 97%

516589

环戊基异氰酸酯

十六烷基异氰酸酯 97%

445401

十六烷基异氰酸酯

3,4-二氯苯异氰酸酯 97%

245607

3,4-二氯苯异氰酸酯

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

density

0.974 g/mL at 25 °C (lit.)

density

0.986 g/mL at 25 °C (lit.)

density

0.861 g/mL at 25 °C (lit.)

density

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

refractive index

n20/D 1.4610 (lit.)

refractive index

n20/D 1.447 (lit.)

refractive index

n20/D 1.448 (lit.)

refractive index

-

bp

193-194 °C (lit.)

bp

147 °C (lit.)

bp

186-188 °C/14 mmHg (lit.)

bp

118-120 °C/18 mmHg (lit.)

免疫原

Peptide sequence around phosphorylation site of serine 32/36 (H-D-S(p)-G-L-D-S(p) -M-K), according to the protein NFKBIA.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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    Lot/Batch Number
    871511152

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    Christin Elßner et al.
    Gastroenterology, 156(4), 1190-1205 (2018-11-18)
    Cholangiocyte proliferation and ductular reaction contribute to the onset and progression of liver diseases. Little is known about the role of the transcription factor nuclear factor-κB (NF-κB) in this process. We investigated the activities of the RELB proto-oncogene NF-κB subunit
    Caiguo Zhang et al.
    Molecular oncology, 12(4), 476-494 (2018-01-30)
    Cullin 4B, a member of the Cullins, which serve as scaffolds to facilitate the assembly of E3 ligase complexes, is aberrantly expressed in many cancers, including osteosarcoma. Recently, we observed that CUL4B forms the CRL4BDCAF11 E3 ligase, which specifically ubiquitinates
    Margherita Leonardi et al.
    Autophagy, 15(2), 312-326 (2018-10-06)
    Macroautophagy/autophagy is one of the major responses to stress in eukaryotic cells and is implicated in several pathological conditions such as infections, neurodegenerative diseases and cancer. Interestingly, cancer cells take full advantage of autophagy both to support tumor growth in

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