跳转至内容
Merck
CN

NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

别名:
IKBA, MAD-3, NFKBI
物种:
UniProtKB ID:
基因ID:
  • Human(4792) Summary: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
  • Mouse(18035) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • Rat(25493) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • naked mole-rat(101709256) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic guinea pig(100723189) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic cat(101090622) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • sheep(780520) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • chicken(396093) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • dog(480291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • cow(282291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-Phospho-IκBα-Ser32/36 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-Phospho-IκBα-S32/36 antibody produced in rabbit, ,
物种反应性
human, mouse
应用
western blot
Anti-p-IκBα-Ser32 Antibody, clone 11D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, feline, human, monkey, porcine
应用
affinity binding assay
flow cytometry

immunocytochemistry

inhibition assay

western blot
Anti-IKB α Antibody, clone 6O8, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

western blot
抗-磷酸化-IkappaB-α(pSer32/36) 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

货号
说明
物种
I?Bα, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Nfkbia,
物种
mouse
MISSION® esiRNA, targeting human NFKBIA,
物种
human