产品名称
抗-CXCR4 兔抗, IgG fraction of antiserum, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human
technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CXCR4(7852)
Biochem/physiol Actions
C-X-C基序趋化因子受体4（CXCR4）对基质细胞衍生因子-1具有特异性。它在调节各种免疫细胞类型的免疫反应中起着至关重要的作用。CXCR4与C4（分化簇4）相互作用，允许人类免疫缺陷病毒1型（HIV-1）进入并感染细胞。该基因中的多态性与少年特发性关节炎（JIA）的发展相关。此外，该基因的突变会增加患心血管疾病（CVD）的风险。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果，我们将给予您完全的赔偿或更换抗体。 了解更多。
General description
C-X-C基序趋化因子受体4 (CXCR4) 由位于人染色体2q22.1的基因编码。该基因编码具有七个跨膜区的蛋白质。编码的蛋白在T-细胞、B-细胞、单核细胞、嗜中性粒细胞和树突细胞表面表达。
Immunogen
CXCR4 抗体，该肽对应于人 CXCR4 氨基末端周围的氨基酸。
Other Notes
可以使用阻断肽 SBP3500383 阻断该抗体的作用。
Physical form
以含有 0.02% 叠氮化钠的 PBS 形式提供。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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The preferential accumulation of vascular smooth muscle cells (vSMCs) on arteries versus veins during early development is a well-described phenomenon, but the molecular pathways underlying this polarization are not well understood. In zebrafish, the cxcr4a receptor (mammalian CXCR4) and its
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