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Merck
CN

CXCR4

chemokine (C-X-C motif) receptor 4

别名:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
物种:
Human CXCR4 (7852), Mouse Cxcr4 (12767), Rat Cxcr4 (60628), cow CXCR4 (281736), domestic guinea pig Cxcr4 (100731341), dog CXCR4 (483900), naked mole-rat Cxcr4 (101699254), sheep CXCR4 (443532), chicken CXCR4 (395324), Domestic Rabbit CXCR4 (100346189)
UniProtKB ID:
P61073, B2R5N0, O60835, P30991, P56438, Q53S69, Q9BXA0, Q9UKN2
基因ID:
  • Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12767) chemokine (C-X-C motif) receptor 4
  • Rat(60628) chemokine (C-X-C motif) receptor 4
  • cow(281736) chemokine (C-X-C motif) receptor 4
  • domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
  • dog(483900) chemokine (C-X-C motif) receptor 4
  • naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
  • sheep(443532) neuropeptide Y receptor type 3
  • chicken(395324) chemokine (C-X-C motif) receptor 4
  • Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
  • domestic cat(493676) chemokine (C-X-C motif) receptor 4

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Antibodies

货号
说明
物种反应性
应用
SAB3500383
抗-CXCR4 兔抗, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
flow cytometry
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
AB1846
Anti-C-X-C Chemokine Receptor 4 Antibody, NT, Chemicon®, from rabbit,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
MABF981
Anti-CXCR4 Antibody, clone 12G5, clone 12G5, from mouse,
物种反应性
human
应用
flow cytometry
immunocytochemistry
neutralization
SAB3501175
Anti-CXCR4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
应用
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
WH0007852M2
Monoclonal Anti-CXCR4 antibody produced in mouse, clone 1F8, ascites fluid,
物种反应性
human
应用
ELISA
western blot

Proteins

货号
说明
物种
HTS004M
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
物种
human

esiRNA

货号
说明
物种
EMU021801
MISSION® esiRNA, targeting mouse Cxcr4,
物种
mouse
EHU022821
MISSION® esiRNA, targeting human CXCR4,
物种
human