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Merck
CN

PHG0006

SAFC

盐酸胍 盐酸盐

制药生产

别名:

亚氨基脲 盐酸盐, 亚氨脲 盐酸盐, 盐酸胍

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About This Item

线性分子式:
NH2C(=NH)NH2 · HCl
CAS号:
分子量:
95.53
Beilstein:
3591990
EC 号:
MDL编号:
UNSPSC代码:
12352107
NACRES:
NA.21

生物来源

synthetic

质量水平

形式

powder

杂质

Endotoxin, microbial, and trace metals; tested

pH值(酸碱度)

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)

溶解性

H2O: 6 M at 20 °C, clear, colorless

密度

1.3 g/cm3 (lit.)

适用性

suitable for manufacturing use

异质活性

Dnase and RNase; tested

SMILES字符串

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

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一般描述

我们的SAFC®高质量原材料产品组合用于生物制药工艺,可通过严苛的质控程序并提供配套文档和技术专长,帮助客户满足 M-Clarity 计划规定的要求。

M-Clarity 计划

我们全面的下游工艺化学品产品组合不仅为生物制药制造商提供生产传统和新型治疗制剂所需的优质原材料,还可帮助他们加速产品上市并简化监管问题。从低风险应用的非 GMP 等级,到高风险应用的 IPEC-PQG GMP标准,我们的产品可满足您的所有制造需求。

应用

强效离液剂,用于蛋白质的变性以及后续复性。该强效变性剂可溶解不溶性或变性的蛋白质,如包涵体。可用作使蛋白质或酶复性为活性形式的第一步骤。可能还需要脲和二硫苏糖醇 (DTT)。

法律信息

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

替代产品

产品编号
说明
价格

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Fackson Mwale et al.
Tissue engineering. Part A, 20(21-22), 2942-2949 (2014-05-03)
Link N is a naturally occurring peptide that can stimulate proteoglycan synthesis in intervertebral disc (IVD) cells. IVD repair can also potentially be enhanced by mesenchymal stem cell (MSC) supplementation to maximize extracellular matrix (ECM) production. In a previous study
Allan Joaquim Lamontanara et al.
Nature communications, 5, 5470-5470 (2014-11-18)
The activity of protein kinases is regulated by multiple molecular mechanisms, and their disruption is a common driver of oncogenesis. A central and almost universal control element of protein kinase activity is the activation loop that utilizes both conformation and
Kym Lowry et al.
PLoS pathogens, 10(6), e1004191-e1004191 (2014-06-20)
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of poliovirus. Despite
Sietse T Braakman et al.
Experimental eye research, 130, 87-96 (2014-12-03)
All aqueous humor draining through the conventional outflow pathway must cross the endothelium of Schlemm's canal (SC), likely by passing through micron-sized transendothelial pores. SC pores are non-uniformly distributed along the inner wall endothelium, but it is unclear how the
Stefan J Kempf et al.
Journal of proteome research, 14(5), 2055-2064 (2015-03-26)
The increased use of radiation-based medical imaging methods such as computer tomography is a matter of concern due to potential radiation-induced adverse effects. Efficient protection against such detrimental effects has not been possible due to inadequate understanding of radiation-induced alterations

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