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Merck
CN

KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

别名:
EAG, EAG1, Kv10.1, h-eag
物种:
UniProtKB ID:
基因ID:
  • Human(3756) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(16510) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Rat(65198) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • cow(281881) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • chicken(421381) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic cat(101093161) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • dog(490277) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Horse(100051219) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • sheep(101120348) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Domestic Rabbit(100340515) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic guinea pig(100719620) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • naked mole-rat(101706330) potassium voltage-gated channel, subfamily H (eag-related), member 1

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Small Molecule - Antagonist

货号
说明
物种
Levofloxacin, 98.0-102.0% anhydrous basis (HPLC),
物种
human
N -去甲基氯氮平, ,
物种
human
司帕沙星, ≥98.0% (HPLC),
物种
human
甲氧苄啶, ≥98.5%,
物种
human, rat
环丙沙星, ≥98% (HPLC),
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
抗-KCNH1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Potassium Channel EAG-1 Antibody, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-Potassium Channel Kv10.1 Antibody, clone 56, clone 56, from mouse,
物种反应性
human, rat
应用
activity assay
immunofluorescence

immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
尼群地平, >95%, powder,
物种
human, rat
匹莫齐特, ,
物种
human, mouse, rat
硝苯地平, ≥98% (HPLC), powder,
物种
rat, mouse, human
盐酸胍 盐酸盐, for molecular biology, ≥99%,
物种
human
盐酸胍 盐酸盐, ≥98%,
物种
human