跳转至内容
Merck
CN

KCNA4

potassium voltage-gated channel, shaker-related subfamily, member 4

别名:
HBK4, HK1, HPCN2, HUKII, KCNA4L, KCNA8, KV1.4, PCN2
物种:
UniProtKB ID:
基因ID:
  • Human(3739) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011]
  • Mouse(16492) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Rat(25469) potassium voltage-gated channel, shaker-related subfamily, member 4
  • cow(281880) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic cat(101084479) potassium voltage-gated channel, shaker-related subfamily, member 4
  • dog(485427) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Zebrafish(559036) potassium voltage-gated channel, shaker-related subfamily, member 4
  • chicken(395721) potassium voltage-gated channel, shaker-related subfamily, member 4
  • naked mole-rat(101706863) potassium voltage-gated channel, shaker-related subfamily, member 4
  • domestic guinea pig(100725985) potassium voltage-gated channel, shaker-related subfamily, member 4
  • Domestic Rabbit(100328568) potassium voltage-gated channel, shaker-related subfamily, member 4
  • sheep(101118217) potassium voltage-gated channel, shaker-related subfamily, member 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-KCNA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-KCNA4 antibody produced in mouse, clone S13-31, 1 mg/mL, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv1.4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
盐酸胍 盐酸盐, for molecular biology, ≥99%,
物种
human
盐酸胍 盐酸盐, ≥98%,
物种
human
盐酸胍 盐酸盐, ≥99% (titration), organic base and chaeotropic agent,
物种
human
盐酸胍 盐酸盐, ,
物种
human
胍 盐酸盐 溶液, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human KCNA4,
物种
human
MISSION® esiRNA, targeting mouse Kcna4,
物种
mouse