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Merck
CN
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文件

50937

Sigma-Aldrich

胍 盐酸盐 溶液

BioUltra, ~8 M in H2O

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别名:
亚氨基脲 盐酸盐, 盐酸胍, 胍盐酸盐
经验公式（希尔记法）:
CH5N3 · HCl
CAS号:
50-01-1
分子量:
95.53
Beilstein:
3591990
MDL编号:
MFCD00013026
UNSPSC代码:
12352107
PubChem化学物质编号:
57651286
NACRES:
NA.25

产品线

BioUltra

质量水平

100

形式

liquid

浓度

~8 M in H2O

杂质

insoluble matter, passes filter test

折射率

n20/D 1.465

pH值（酸碱度）

4.5-7.5 (25 °C)

痕量阴离子

sulfate (SO42-): ≤50 mg/kg

痕量阳离子

Al: ≤1 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤60 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

neat

紫外吸收

λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.025

SMILES字符串

Cl.NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

基因信息

human ... KCNA1(3736) , KCNA10(3744) , KCNA2(3737) , KCNA3(3738) , KCNA4(3739) , KCNA5(3741) , KCNA6(3742) , KCNA7(3743) , KCNB1(3745) , KCNB2(9312) , KCNC1(3746) , KCNC2(3747) , KCNC3(3748) , KCNC4(3749) , KCND1(3750) , KCND2(3751) , KCND3(3752) , KCNF1(3754) , KCNG1(3755) , KCNG2(26251) , KCNG3(170850) , KCNG4(93107) , KCNH1(3756) , KCNH2(3757) , KCNH3(23416) , KCNH4(23415) , KCNH5(27133) , KCNH6(81033) , KCNH7(90134) , KCNH8(131096) , KCNQ1(3784) , KCNQ2(3785) , KCNQ3(3786) , KCNQ4(9132) , KCNQ5(56479) , KCNS1(3787) , KCNS2(3788) , KCNS3(3790) , KCNV1(27012) , KCNV2(169522)

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相关类别

应用

盐酸胍溶液已被用作固定缓冲液，用于基因组分析中基因组DNA的提取。

生化/生理作用

盐酸胍（Gnd-HCl）是一种高效的离液剂（chaotropic agent），作为变性剂被广泛用于RNA分离、球蛋白变性和蛋白质复性研究。它是一种合适的样品缓冲剂，可用于亲和纯化的蛋白质复合物的快速有效的洗脱，以及之后的蛋白质消化步骤。由于其在低摩尔浓度下抑制胰蛋白酶活性，并且在与十二烷基硫酸钠（SDS）结合时有形成沉淀的倾向，盐酸胍不适用于蛋白质组学实验。盐酸胍常用于从富含细胞外基质（ECM）‐的组织（包括骨骼、软骨、韧带和肌腱）中提取蛋白质。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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