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Merck
CN

50937

Sigma-Aldrich

胍 盐酸盐 溶液

BioUltra, ~8 M in H2O

别名:

亚氨基脲 盐酸盐, 盐酸胍, 胍盐酸盐

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About This Item

经验公式(希尔记法):
CH5N3 · HCl
CAS号:
分子量:
95.53
Beilstein:
3591990
MDL编号:
UNSPSC代码:
12352107
PubChem化学物质编号:
NACRES:
NA.25

产品线

BioUltra

质量水平

表单

liquid

浓度

~8 M in H2O

杂质

insoluble matter, passes filter test

折射率

n20/D 1.465

pH值(酸碱度)

4.5-7.5 (25 °C)

痕量阴离子

sulfate (SO42-): ≤50 mg/kg

痕量阳离子

Al: ≤1 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤10 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mg: ≤5 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤150 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

neat

紫外吸收

λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.025

SMILES字符串

Cl.NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

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应用

盐酸胍溶液已被用作固定缓冲液,用于基因组分析中基因组DNA的提取。

生化/生理作用

盐酸胍(Gnd-HCl)是一种高效的离液剂(chaotropic agent),作为变性剂被广泛用于RNA分离、球蛋白变性和蛋白质复性研究。它是一种合适的样品缓冲剂,可用于亲和纯化的蛋白质复合物的快速有效的洗脱,以及之后的蛋白质消化步骤。由于其在低摩尔浓度下抑制胰蛋白酶活性,并且在与十二烷基硫酸钠(SDS)结合时有形成沉淀的倾向,盐酸胍不适用于蛋白质组学实验。盐酸胍常用于从富含细胞外基质(ECM)‐的组织(包括骨骼、软骨、韧带和肌腱)中提取蛋白质。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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