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Merck
CN

N0505

Sigma-Aldrich

β-烟酰胺腺嘌呤二核苷酸磷酸 水合物

别名:

三磷酸吡啶核苷酸 钠盐 水合物

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About This Item

经验公式(希尔记法):
C21H27N7NaO17P3 · xH2O
分子量:
765.39 (anhydrous basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

检测方案

≥98% (HPLC)
≥98% (spectrophotometric assay)

质量水平

形式

powder

mp

175-178 °C (dec.) (lit.)

溶解性

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

储存温度

−20°C

SMILES字符串

O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]

InChI

1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1

InChI key

CYQLUFJYVTUUFN-WUEGHLCSSA-M

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生化/生理作用

电子受体

包装

根据固体质量包装。

其他说明

这是 NADP 的常见形式。不要与 3′-NADP 或 α-NADP 混淆。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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F Moreno et al.
European journal of biochemistry, 161(3), 565-569 (1986-12-15)
Hexokinase PII is not inhibited by high Mg-ATP concentrations if the Mg2+-free ATP is kept at low levels (0.01 mM) in the assay mixture. Hexokinase PI activity is not affected either by Mg2+-free ATP nor by free Mg2+ in the
Syaghalirwa N M Mandiki et al.
Steroids, 70(2), 85-94 (2005-01-06)
Sex steroid inhibitors were used to characterize the effects of 17beta-estradiol (E2) and testosterone (T) on the sexual growth dimorphism of Eurasian perch juveniles. In experiment 1, growth responses to different doses of either E2 (25, 50, 75, and 100
David J Waxman et al.
Methods in molecular biology (Clifton, N.J.), 320, 91-96 (2006-05-25)
A spectrofluorometric method is described for the determination of CYP2A6-catalyzed coumarin 7-hydroxylation. Following acidification of the reaction mixture, the enzymatic product, 7-hydroxycoumarin, is recovered by a double-extraction procedure and assayed using an excitation wavelength of 370 nm and an emission
Jianneng Li et al.
Science translational medicine, 13(595) (2021-05-28)
Prostate cancer resistance to next-generation hormonal treatment with enzalutamide is a major problem and eventuates into disease lethality. Biologically active glucocorticoids that stimulate glucocorticoid receptor (GR) have an 11β-OH moiety, and resistant tumors exhibit loss of 11β-HSD2, the oxidative (11β-OH
Considine, DM et al.
Van Nostrand Reinhold Encyclopedia of Chemistry, 1993-1993 null

实验方案

Measure hexokinase activity using a continuous spectrophotometric rate-determination assay at 340 nm, catalyzing D-hexose sugar phosphorylation using ATP.

在测定己糖激酶活性时,使用了一种在340nm处的连续分光光度法进行测定。己糖激酶使用ATP作为磷酸的来源来催化D-己糖的磷酸化。

在测定6-磷酸葡萄糖脱氢酶活性时,使用β-烟酰胺腺嘌呤二核苷酸磷酸在340 nm处通过分光光度法进行测定。

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

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