推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen ~280 kDa
antigen ~72 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
flow cytometry: 1:200-1:500
immunohistochemistry: 1:100-1:200
western blot: 1:500-1:1,000
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MAP2(4133)
mouse ... Mtap2(17756)
rat ... Map2(25595)
相关类别
一般描述
MAP2 是一种与微管相关的蛋白，调节细胞骨架的结构和功能。该蛋白也调节神经元的形态发生和细胞增殖。MAP2和F-actin的相互作用与神经突初生（neurite initiation）和微管再组装有关。MAP2 的水平下降与传染性海绵状脑病相关。抗MAP2抗体对于人、小鼠和大鼠MAP2有特异性。
微管相关蛋白 2 (Microtubule associated protein 2，MAP2) 是一种神经元特异性蛋白，在中枢神经系统中广泛表达。它是细胞骨架蛋白中的一员。 该基因位于人类染色体 2q34 上。
免疫原
相应的人 MAP2 残基 2-15 的合成肽。
应用
兔抗 MAP2 抗体可用于免疫细胞化学。
抗 MAP2 抗体适用于免疫组织化学（1:500，使用 Zamboni 固定剂固定、冷冻的小鼠脊髓和丘脑切片）、流式细胞术 (1:200-1:500)、免疫印迹（约 72 kDa 和 280 kDa）和蛋白质印迹 (1:500-1:1,000)。
生化/生理作用
微管相关蛋白2（MAP2）在星形胶质细胞和少突胶质细胞中树突状突起的形成过程中起关键作用。它可以维持微管的稳态。该蛋白在神经可塑性中起重要作用。
外形
溶剂为含有0.02％叠氮化钠的磷酸盐缓冲盐水。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
推荐
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
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