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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

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主要文件

L4395

Sigma-Aldrich

脂质体试剂盒:用于制备脂质体的脂质混合物

lyophilized powder

别名:

cholesterol, L-α-phosphatidylcholine and stearylamine kit

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100 μL
¥5,551.31

¥5,551.31


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100 μL
¥5,551.31

About This Item

EC 号:
UNSPSC代码:
12352211
NACRES:
NA.25

¥5,551.31


请联系客服了解存货情况

获取大包装报价

生物来源

egg yolk

质量水平

表单

lyophilized powder

组成

Cholesterol, 9 μmol/package
L-α-Phosphatidylcholine (egg yolk), 63 μmol/package
Stearylamine, 18 μmol/package

官能团

carboxylic acid

运输

ambient

储存温度

−20°C

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1 of 4

此商品
HPA042634HPA043059HPA053160
antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

Prestige Antibodies® Powered by Atlas Antibodies

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

应用

脂质体试剂盒用于制备脂质体。[1][2][3]

生化/生理作用

脂质体可用于不同的应用,例如药物递送、诊断、膜模型、疫苗接种佐剂等。这种脂质混合物可用于封装各种低分子量、中等分子量和高分子量的亲水和两亲分子(包括肽、蛋白质以及寡核苷酸和多核苷酸)。
脂质体试剂盒:用于制备脂质体的脂质混合物含有胆固醇;L-α-磷脂酰胆碱和硬脂胺。 脂质体试剂盒可用于制备阳离子(带正电荷)脂质体,用于将材料掺入细胞中。

相关产品

象形图

CorrosionEnvironment

警示用语:

Danger

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

  • 技术规格说明书

  • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    1. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    2. How do I get lot-specific information or a Certificate of Analysis?

      The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    3. I have purchased Product L4395, Liposome Kit.  Is there a difference between positive and negative liposomes?

      The choice is dependent upon what is being encapsulated and how it is being used.  A good reference discussing this question is Ogiso, T., et al., Effect of positively and negatively charged liposomes on skin permeation of drugs. J. Drug Target, 9(1), 49-59 (2001).

    4. How is Product L4395, Liposome Kit, used?

      The Liposomes of a large multilamellar structure type are the most widely used. They can be prepared using Sigma liposome mixtures by concentrating an organic solvent solution of lipids to a thin film on the walls of a container such as by rotary evaporation or by drying in glass with a stream of nitrogen gas. Then, under appropriate conditions, an aqueous solution is added to the thin film and with agitation multilamellar vesicles should form spontaneously with little effort. Large or small unilamellar structured liposomes can also be prepared by varying procedure or conditions. Please see the product insert for Product No. L4031 (the link below) for a step by step protocol that will work for this product also.

    5. How do I prepare the Product L4395, Liposome Kit liposomes?

      Refer to the product information sheet (under Documents, above) for L4031 for preparation information.

    6. I'm thinking of purchasing Product L4395, Liposome Kit.  Why would one use positive vs. negative liposomes?

      Analogous to poly-L-lysine, one may need positively charged agents to deliver drugs to cells, hence positive liposomes.

    7. How do I find price and availability?

      There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

    8. What is the Department of Transportation shipping information for this product?

      Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

    9. My question is not addressed here, how can I contact Technical Service for assistance?

      Ask a Scientist here.

    Rui Xu et al.
    Analytical chemistry, 88(21), 10390-10394 (2016-11-02)
    Chemical analysis of small extracellular vesicles (sEVs) circulating in body fluids holds potentials in noninvasive diagnosis of diseases and evaluation of therapeutic treatments. However, quantification of sEVs remains a challenge due to lacking of cost-effective analytical protocols. Herein we report
    Quantification of small extracellular vesicles by size exclusion chromatography with fluorescence detection
    Xu R, et al.
    Analytical Chemistry, 88(21), 10390-10394 (2016)
    Sub-Micrometric Liposomes as Drug Delivery Systems in the Treatment and Periodontitis
    Di Turi G, et al.
    International Journal of Immunopathology and Pharmacology, 25(3), 657-670 (2012)
    G T Köse et al.
    Drug delivery, 5(4), 257-264 (1998-01-01)
    Multilamellar vesicles (MLV) containing phosphatidyl choline (PC), cholesterol (CHOL), and stearylamine (SA) in the molar ratio of 7:2:0.2 were prepared by the thin film hydration method. Low-molecular-weight heparin (LMWH, MW: 3000) was conjugated with the MLV using carbodiimide (EDC). Infrared
    Xuan T A Nguyen et al.
    Molecular neurobiology, 56(9), 6121-6133 (2019-02-08)
    The cellular prion protein (PrPC), mainly known for its role in neurodegenerative diseases, is involved in several physiological processes including neuritogenesis. In addition, its ability to bind copper or zinc has been suggested for its role in metal homeostasis. Although

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