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文件

G8541

丙氨酸-谷氨酰胺

Name: 丙氨酸-谷氨酰胺
Brand: SIGMA

200 mM, solution, sterile-filtered, Biotechnology Performance Certified

别名:

丙氨酰谷氨酰胺, 丙谷二肽

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About This Item

经验公式（希尔记法）:

C₈H₁₅N₃O₄

CAS号:

39537-23-0

分子量:

217.22

MDL编号:

MFCD00133046

UNSPSC代码:

12352209

PubChem化学物质编号:

24895343

NACRES:

NA.75

等级

Biotechnology Performance Certified

质量水平

400

无菌性

sterile-filtered

形式

solution

浓度

200 mM

杂质

endotoxin, tested

储存温度

2-8°C

SMILES字符串

NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O

InChI

1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1

InChI key

HJCMDXDYPOUFDY-WHFBIAKZSA-N

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一般描述

Ala-Gln 补充剂在溶液中提供稳定形式的 L-谷氨酰胺。

应用

Ala-Gln 已被用作富含葡萄糖和丙酮酸的 Dulbecco′s 改良 Eagle 培养基（DMEM）中的补充剂，以培养表达荧光素酶的 MDA-MB-231-luc 肿瘤细胞，从而测量在从解剖的长骨进行骨髓内移植（IBMT）期间泄漏的细胞的生物发光信号。它也被用作 DMEM-高葡萄糖培养基来培养人类细胞系。

其他说明

含二肽 L-丙氨酰-L-谷氨酰胺。200mM 溶液中添加 0.85% NaCl。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Capacity of the medullary cavity of tibia and femur for intra-bone marrow transplantation in mice.

Dieter Fink et al.

PloS one, 14(11), e0224576-e0224576 (2019-11-08)

Intra-bone marrow transplantation (IBMT) has been adapted for mouse models to improve the seeding efficiency of transplanted hematopoietic stem and progenitor cells. Commonly used injection volumes for IBMT into the tibia differ between 10 and 40 μL even though considerable

Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial.

Daren K Heyland et al.

JPEN. Journal of parenteral and enteral nutrition, 39(4), 401-409 (2014-05-08)

The recent large randomized controlled trial of glutamine and antioxidant supplementation suggested that high-dose glutamine is associated with increased mortality in critically ill patients with multiorgan failure. The objectives of the present analyses were to reevaluate the effect of supplementation

Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues.

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In contrast to single-cell approaches for measuring gene expression and DNA accessibility, single-cell methods for analyzing histone modifications are limited by low sensitivity and throughput. Here, we combine the CUT&Tag technology, developed to measure bulk histone modifications, with droplet-based single-cell

Structure and Function of the Bacterial Protein Toxin Phenomycin.

Bente K Hansen et al.

Structure (London, England : 1993), 28(5), 528-539 (2020-03-30)

Phenomycin is a bacterial mini-protein of 89 amino acids discovered more than 50 years ago with toxicity in the nanomolar regime toward mammalian cells. The protein inhibits the function of the eukaryotic ribosome in cell-free systems and appears to target translation

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Hiroshi Ono et al.

Cancer medicine, 3(3), 632-642 (2014-03-05)

Small-cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis. To identify accurate predictive biomarkers and effective therapeutic modalities, we focus on a long noncoding RNA, Hox transcript antisense intergenic RNA (HOTAIR), and investigated its expression, cellular

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