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G7879

D-葡萄糖-6-磷酸 钠盐

≥98% (HPLC)

别名:

D(+)-葡糖醛糖6-磷酸 钠盐, G-6-P Na, 鲁氏酯

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关于此项目

经验公式（希尔记法）:
C6H12NaO9P
化学文摘社编号:
54010-71-8
分子量:
282.12
MDL number:
MFCD00006611
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24895324
EC Number:
258-921-0
Beilstein/REAXYS Number:
5787568
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biological source

synthetic (organic)

Quality Level

300

assay

≥98% (HPLC)

form

crystalline

technique(s)

HPLC: suitable

color

white

useful pH range

4.0-5.0

mp

204 °C (dec.) (lit.)

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

cation traces

Na: 6.1-10.2% (anhydrous)

application(s)

advanced drug delivery

storage temp.

room temp

SMILES string

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

InChI key

ZALKNDISPIVVKC-WYRLRVFGSA-M

Application

D-葡萄糖-6-磷酸钠可用作结核分枝杆菌的能源。

Biochem/physiol Actions

在细胞中，当葡萄糖被己糖激酶或葡萄糖激酶磷酸化，或在糖原分解过程中磷酸葡萄糖变位酶将 1-磷酸葡萄糖转化时，会生成 D-葡萄糖 6-磷酸（G6P）。G6P 位于糖酵解和磷酸戊糖途径的起始阶段。当血糖水平高时，它也可以作为糖原储存。

Other Notes

为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。

Disclaimer

与二钠盐不同，它不吸湿，并且在室温下对大气湿度非常稳定。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000550185
0000550184
0000550184
0000550185
0000494323

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实验方案

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

6-磷酸葡萄糖脱氢酶（EC 1.1.1.49）的酶学测定

在测定6-磷酸葡萄糖脱氢酶活性时，使用β-烟酰胺腺嘌呤二核苷酸磷酸在340 nm处通过分光光度法进行测定。

商品

Aerobic Glycolysis and the Warburg Effect

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

需氧糖酵解和瓦博格效应

本页面介绍了一篇有关瓦博格效应的文章，以及其如何能够在正常氧气水平下，增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明，癌细胞显示出对糖酵解的依赖性增加，以满足他们的能量需求，无论是否有充足的氧气存在。

Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Iain J Abbott et al.
The Journal of antimicrobial chemotherapy, 75(4), 988-996 (2019-12-25)
To assess the antibacterial effects of a single 3 g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model. An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(3) (2020-01-08)
Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and any benefit of giving multiple
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全球贸易项目编号

货号GTIN
G7879-5G04061835366903
G7879-500MG04061835366897
G7879-25G04061835366880
G7879-1G04061835366873