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Merck
CN

D7909

Dicyclomine hydrochloride

≥99% (TLC), powder

别名:

2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride

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关于此项目

经验公式（希尔记法）:
C19H35NO2 · HCl
化学文摘社编号:
67-92-5
分子量:
345.95
NACRES:
NA.77
PubChem Substance ID:
24278385
UNSPSC Code:
41116107
EC Number:
200-671-1
MDL number:
MFCD00079158
Assay:
≥99% (TLC)
Form:
powder
Quality level:
200

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产品名称

Dicyclomine hydrochloride, ≥99% (TLC), powder

InChI key

GUBNMFJOJGDCEL-UHFFFAOYSA-N

InChI

1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H

SMILES string

CCN(CCOC(C1(C2CCCCC2)CCCCC1)=O)CC.[Cl]

assay

≥99% (TLC)

form

powder

color

off-white

solubility

H2O: 50 mg/mL

Quality Level

200

Gene Information

human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

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Biochem/physiol Actions

Competitive muscarinic acetylcholine receptor antagonist.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000476397
0000459460
0000459460
0000476397
0000311404

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Christopher D Cox et al.
Journal of neurotrauma, 25(11), 1355-1365 (2008-12-09)
Recent studies indicate that alphaII-spectrin breakdown products (SBDPs) have utility as biological markers of traumatic brain injury (TBI). However, the utility of SBDP biomarkers for detecting effects of therapeutic interventions has not been explored. Acetylcholine plays a role in pathological
Susan J Bartko et al.
Psychopharmacology, 214(2), 537-548 (2010-11-19)
Performance on the Cambridge Neuropsychological Test Automated Battery touchscreen paired-associates learning (PAL) test is predictive of Alzheimer's disease and impaired in schizophrenia and chronic drug users. An automated computer touchscreen PAL task for rats has been previously established. A pharmacologically
American Gastroenterological Association institute medical position statement on the use of gastrointestinal medication in pregnancy.
Arthur Staroselsky et al.
Gastroenterology, 132(2), 824-825 (2007-01-31)
Andrea M Robinson et al.
Journal of psychopharmacology (Oxford, England), 26(8), 1143-1150 (2011-09-06)
The cholinergic system is known to be necessary for normal attentional processing. However, the receptors and mechanisms mediating the effects of acetylcholine on attention remain unclear. Previous work in our laboratory suggested that cholinergic muscarinic receptors are critical for maintaining
K-W Lee et al.
Neuroscience, 153(4), 1235-1244 (2008-05-06)
Muscarinic acetylcholine receptors (M1-M5) regulate many key functions of the CNS and peripheral nervous system. In the present study, the role of M1 muscarinic receptors (M1R) in the psychomotor stimulant and sensitizing properties of methamphetamine (METH) is investigated using molecular
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