D7909
Dicyclomine hydrochloride
≥99% (TLC), powder
别名:
2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride
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关于此项目
经验公式（希尔记法）:
C19H35NO2 · HCl
化学文摘社编号:
分子量:
345.95
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥99% (TLC)
表单
powder
颜色
off-white
溶解性
H2O: 50 mg/mL
SMILES字符串
CCN(CCOC(C1(C2CCCCC2)CCCCC1)=O)CC.[Cl]
InChI
1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H
InChI key
GUBNMFJOJGDCEL-UHFFFAOYSA-N
基因信息
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
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生化/生理作用
Competitive muscarinic acetylcholine receptor antagonist.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Nav Persaud et al.
The International journal of risk & safety in medicine, 24(1), 31-35 (2012-03-23)
Until recently epidemiological evidence was not regarded as helpful in determining cause and effect. It generated associations that then had to be explained in terms of bio-mechanisms and applied to individual patients. A series of legal cases surrounding possible birth
Z W Jiang et al.
Brain research, 852(1), 37-44 (2000-02-08)
The rat subdural hematoma (SDH) model produces a zone of ischemic brain damage within the hemisphere beneath the SDH. Previous studies have measured large increases in extracellular acetylcholine during cerebral ischemia in the rat. We examined infarct volume after selectively
Surabi Veeraragavan et al.
Psychopharmacology, 217(1), 143-151 (2011-04-14)
Muscarinic acetylcholine receptors (mAChR) are G protein-coupled receptors, widely expressed in the CNS. Electrophysiological and molecular studies have provided evidence for overactive M1 receptor signaling in the fragile X knockout (Fmr1 KO) mouse model, suggesting the involvement of the M1
Susan J Bartko et al.
Psychopharmacology, 214(2), 537-548 (2010-11-19)
Performance on the Cambridge Neuropsychological Test Automated Battery touchscreen paired-associates learning (PAL) test is predictive of Alzheimer's disease and impaired in schizophrenia and chronic drug users. An automated computer touchscreen PAL task for rats has been previously established. A pharmacologically
Christopher D Cox et al.
Journal of neurotrauma, 25(11), 1355-1365 (2008-12-09)
Recent studies indicate that alphaII-spectrin breakdown products (SBDPs) have utility as biological markers of traumatic brain injury (TBI). However, the utility of SBDP biomarkers for detecting effects of therapeutic interventions has not been explored. Acetylcholine plays a role in pathological
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