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Merck
CN

D7644

丙吡胺

别名:

双异丙吡胺

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经验公式(希尔记法):
C21H29N3O
化学文摘社编号:
分子量:
339.47
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
223-110-2
MDL number:
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InChI key

UVTNFZQICZKOEM-UHFFFAOYSA-N

InChI

1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)

SMILES string

CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C

Gene Information

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Biochem/physiol Actions

IA 类抗心律失常药;钠通道阻断剂

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J P Fauchier et al.
Archives des maladies du coeur et des vaisseaux, 84(4), 553-560 (1991-04-01)
Moricizine chlorhydrate (Ethmozine), a relatively unknown antiarrhythmic agent in France, is a derivative of Phenothiazine, related to the Vaughan-Williams Class IB drugs. A randomised, double-blind, crossover trial with Disopyramide 600 mg/day after a placebo period in 10 patients with ventricular
Katsuya Kajimoto et al.
The American journal of cardiology, 106(9), 1307-1312 (2010-10-30)
Negative inotropic agents are often administered to decrease the left ventricular (LV) pressure gradient in patients with obstructive hypertrophic cardiomyopathy (HC). Little information is available regarding comparisons of the effects on LV pressure gradient among negative inotropic agents. The present
Procainamide and disopyramide.
C Ribeiro et al.
European heart journal, 8 Suppl A, 11-19 (1987-03-01)
Pharmacokinetics and pharmacodynamics of disopyramide.
J Bonde
Danish medical bulletin, 38(2), 121-133 (1991-04-01)
R N Brogden et al.
Drugs, 34(2), 151-187 (1987-08-01)
Disopyramide is a widely used class IA antiarrhythmic drug with a pharmacological profile of action similar to that of quinidine and procainamide. Over the past 10 years disopyramide has demonstrated its efficacy in ventricular and atrial arrhythmias. In therapeutic trials

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