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Merck
CN

ADD670C

HepaRG Thawing and Plating Medium Supplement with Antibiotics

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NACRES:
NA.71
UNSPSC Code:
12352207
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form

liquid

shipped in

dry ice

storage temp.

−20°C

Application

HepaRG Thawing and Plating Medium Supplement with Antibiotics has been used as a supplement to culture HepaRG cells.

General description

Biopredic′s HepaRG Thawing and Plating Medium Supplement with Antibiotics can be used with all HepaRG cell lines.
HepaRG cells have the unique properties of maintaining significant levels of hepatic cell functions, of being CYP450 inducible, and supporting the complete replicative cycle of HBV.
HepaRG cells have the unique properties of maintaining significant levels of hepatic cell functions, being cytochrome P450 (CYP450) inducible, and supporting the complete replicative cycle of hepatitis B virus (HBV).

Legal Information

Use of this product is subject to one or more license agreements.

HepaRG cells are patented and their use is strictly limited; consider the cells as a single use, disposable product that must be destroyed upon conclusion of a study or experiment. Propagating, reproducing, cloning, subcloning or any other use of the cells following the conclusion of a study is prohibited. Use of the cells to produce or manufacture commercial products for general sale or for use in the manufacture of products intended for general sale is prohibited. Transfer of the cells to anyone not employed within the same organization, whether for financial benefit or not, is prohibited. If you are unwilling to accept the terms of this LIMITED USE LICENSE, do not ORDER or use them and immediately return the cells for credit. Violators of this Limited Use Licesense will be prosecuted to the fullest extent of the law.
HepaRG is a trademark of BioPredic International company

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Robin Mesnage et al.
Archives of toxicology, 92(8), 2533-2547 (2018-06-28)
Chemical pollutant exposure is a risk factor contributing to the growing epidemic of non-alcoholic fatty liver disease (NAFLD) affecting human populations that consume a western diet. Although it is recognized that intoxication by chemical pollutants can lead to NAFLD, there
Robin Mesnage et al.
Toxicology reports, 5, 819-826 (2018-08-22)
Use and thus exposure to quizalofop-p-ethyl, isoxaflutole, mesotrione and glyphosate, which are declared as active principles in commercial formulations of herbicides, is predicted to rapidly increase in coming years in an effort to overcome the wide-spread appearance of glyphosate-resistant weeds
Catherine C Bell et al.
Drug metabolism and disposition: the biological fate of chemicals, 45(4), 419-429 (2017-02-01)
Reliable and versatile hepatic in vitro systems for the prediction of drug pharmacokinetics and toxicity are essential constituents of preclinical safety assessment pipelines for new medicines. Here, we compared three emerging cell systems-hepatocytes derived from induced pluripotent stem cells, HepaRG
Beth Williamson et al.
Pharmacology research & perspectives, 4(5), e00264-e00264 (2016-10-08)
The nuclear pregnane X receptor (PXR) regulates the expression of genes involved in the metabolism, hepatobiliary disposition, and toxicity of drugs and endogenous compounds. PXR is a promiscuous nuclear hormone receptor (NHR) with significant ligand and DNA-binding crosstalk with the
Yi Ni et al.
Methods in molecular biology (Clifton, N.J.), 1540, 15-25 (2016-12-16)
Investigations of virus-host interactions rely on suitable in vitro cell culture systems that efficiently support virus infection. Such systems should ideally provide conditions that resemble those of natural host cells, e.g., the cell-type specific signaling and metabolic pathways. For HBV

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