所有图片(1)
About This Item
经验公式（希尔记法）:
C5H9NO2
CAS号:
分子量:
115.13
Beilstein:
1721512
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
推荐产品
方案
≥99% (TLC)
表单
powder
旋光性
[α]25/D −37.1°, c = 4 in H2O(lit.)
颜色
white
溶解性
H2O: 100 mg/mL
储存温度
room temp
SMILES字符串
N[C@@H](CC=C)C(O)=O
InChI
1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8)/t4-/m0/s1
InChI key
WNNNWFKQCKFSDK-BYPYZUCNSA-N
基因信息
human ... GAD1(2571) , GAD2(2572)
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生化/生理作用
Glutamic acid decarboxylase inhibitor.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
J Thomas et al.
Physiology & behavior, 49(6), 1181-1183 (1991-06-01)
The possibility that a sex difference in gamma-aminobutyric acid (GABA) activity might be an underlying cause of the previously reported sex differences in picrotoxin-induced seizures was investigated. Male and female rats were injected (IP) with the GABA antagonist, L-allylglycine (100
V M Abshire et al.
Neuropharmacology, 27(11), 1171-1177 (1988-11-01)
Injection of the GABA antagonist, bicuculline methiodide into the posterior hypothalamus of rats has been shown to cause marked increases in heart rate and lesser elevations in blood pressure. Allylglycine is a potent inhibitor of the synthetic enzyme for GABA
M Bottlaender et al.
European journal of pharmacology, 321(1), 13-17 (1997-02-19)
The influence of decreased endogenous gamma-aminobutyric acid (GABA) concentration on benzodiazepine receptor function was studied in the brain of living baboons. Positron emission tomography and the radiotracer [11C]flumazenil combined with electroencephalography were used to determine the pharmacological properties of two
M Iijima et al.
British journal of pharmacology, 171(14), 3511-3525 (2014-03-25)
Vasopressin V1B receptor antagonists may be effective for the treatment of depression and anxiety and the objective of this study was to characterize the pharmacological profiles of two newly synthesized arginine vasopressin receptor 1B (V1B receptor) antagonists, TASP0233278 and TASP0390325.
Tracie A Paine et al.
Pharmacology, biochemistry, and behavior, 135, 97-104 (2015-06-06)
Cortical GABA regulates a number of cognitive functions including attention and working memory and is dysregulated in a number of psychiatric conditions. In schizophrenia for example, changes in GABA neurons [reduced expression of glutamic acid decarboxylase (GAD), parvalbumin (PV) and
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