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GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

别名:
GAD65
物种:
UniProtKB ID:
基因ID:
  • Human(2572) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
  • Mouse(14417) glutamic acid decarboxylase 2
  • Rat(24380) glutamate decarboxylase 2
  • domestic guinea pig(100734029) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • naked mole-rat(101698166) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Thale Cress(842908) glutamate decarboxylase 2
  • sheep(101106448) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • chicken(395395) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • dog(487107) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • domestic cat(101082244) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • cow(512459) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Zebrafish(550403) glutamate decarboxylase 2

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Antibodies

货号
说明
物种反应性
应用
Anti-Glutamate Decarboxylase 65 & 67 Antibody, Chemicon®, from rabbit,
物种反应性
feline, human, mouse, rat
应用
immunohistochemistry
western blot
抗谷氨酸脱羧酶抗体,65 kDa亚型,克隆GAD-6, clone GAD-6, Chemicon®, from mouse,
物种反应性
human, rat
应用
immunohistochemistry
western blot
Anti-GAD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-GAD65 Antibody, clone 3B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-Glutamate Decarboxylase Antibody, 65 kDa isoform, clone GAD-6, clone GAD-6, Chemicon®, from mouse,
物种反应性
human, rat
应用
immunohistochemistry
western blot

Proteins

货号
说明
物种
GAD, control peptide for AB1511, ,
物种
rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GAD2,
物种
human
MISSION® esiRNA, targeting mouse Gad2,
物种
mouse