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Merck
CN

89510

聚(乙二醇)

greener alternative

BioUltra, 8,000

别名:

PEG

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关于此项目

线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:
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产品名称

聚(乙二醇), BioUltra, 8,000

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES string

C(CO)O

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

solid

mol wt

Mr 7000-9000

Quality Level

cation traces

Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

61-64 °C

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.09
λ: 280 nm Amax: 0.03

greener alternative category

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Application

聚乙二醇已被用于:
  • 酵母的转化缓冲液
  • 作为登革病毒分离缓冲液的成分
  • 慢病毒颗粒的浓缩
  • 疱疹病毒核出口复合物(NEC)的结晶化

Biochem/physiol Actions

美国食品和药品监督管理局(FDA)批准PEG用作药物结合物,它是非免疫原性且安全的。PEG被广泛用作生物化学和分子生物学实验的试剂。PEG结合改善了糖尿病药物格列齐特的溶解度和溶出度。它被用于碳纳米管官能化。在富含单宁的树叶中,PEG 8000的存在可提高代谢能(ME)含量和气体产生。

General description

聚乙二醇(PEG)是乙二醇聚合物,具有亲水性。PEG具有高水合能力并且结构灵活。由于PEG具有生物相容性并且结构中不存在空间位阻,因此,它在用作药物结合物方面具有优势。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A simple, inexpensive, robust and sensitive dot-blot assay for equal detection of the nonstructural-1 glycoprotein of all dengue virus serotypes
Falconar AK and Romero-Vivas CM
Virology Journal, 10(1), 126-126 (2013)
The effect of polyethylene glycol (PEG 8000) supplementation on in vitro gas production kinetics of leaves from tannin containing trees
Kamalak A, et al.
South African Journal of Animal Science, 35(4), 229-237 (2005)
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions
Zhang C, et al.
Scientific Reports, 7(1), 44708-44708 (2017)
Characterisation of gliclazide-PEG 8000 solid dispersions
Biswal S, et al.
Tropical Journal of Pharmaceutical Research, 8(5) (2009)
Ananthakrishnan Soundaram Jeevarathinam et al.
Biosensors & bioelectronics, 126, 831-837 (2019-01-04)
Heparin is an indispensable drug in anticoagulation therapy but with a narrow therapeutic window, which dictates regular testing and dose adjustment. However, current monitoring tools have a long turnaround time or are operator intensive. In this work, we describe a

相关内容

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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