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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

We are planning system maintenance between Friday, Apr 11 at 9:00 PM CDT and Saturday, Apr 12 at 9:00 AM CDT. This will impact both web and offline transactions, including online orders, quotes, price and availability checks, and order status inquiries. We apologize for any inconvenience.

Merck
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主要文件

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安全信息

C0750

Sigma-Aldrich

咖啡因

powder, ReagentPlus®

别名:

1,3,7-三甲基黄嘌呤

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About This Item

经验公式（希尔记法）:
C8H10N4O2
CAS号:
58-08-2
分子量:
194.19
Beilstein:
17705
EC 号:
200-362-1
MDL编号:
MFCD00005758
UNSPSC代码:
12352210
PubChem化学物质编号:
24277682
NACRES:
NA.21
价格与库存信息目前不能提供

质量水平

200

产品线

ReagentPlus®

表单

powder

mp

234-236.5 °C (lit.)

溶解性

H2O: 15 mg/mL

SMILES字符串

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

基因信息

human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140) , PDE4B(5142) , PRKAR1A(5573) , PRKAR1AP(5574) , PRKAR1B(5575) , PRKAR2A(5576) , PRKAR2B(5577)
mouse ... Adora2b(11541)
rat ... Adora1(29290) , Adora2a(25369)

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此商品
3355316037P57506M
Pyridine anhydrous, 99.8%

270970

Pyridine

Pyridine puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99.5% (GC)

33553

Pyridine

Pyridine ≥99.5% (GC)

16037

Pyridine

Pyridine reagent grade, ≥99%

P57506M

Pyridine

grade

anhydrous

grade

ACS reagent, puriss. p.a.

grade

-

grade

reagent grade

Quality Level

200, 300

Quality Level

200

Quality Level

-

Quality Level

-

form

liquid

form

liquid

form

liquid

form

liquid

vapor pressure

10 mmHg ( 13.2 °C), 20 mmHg ( 25 °C)

vapor pressure

10 mmHg ( 13.2 °C), 20 mmHg ( 25 °C)

vapor pressure

10 mmHg ( 13.2 °C), 20 mmHg ( 25 °C)

vapor pressure

10 mmHg ( 13.2 °C), 20 mmHg ( 25 °C)

pH

~8.81 (20 °C)

pH

8.5 (25 °C, 15.82 g/L)

pH

-

pH

8.5 (25 °C, 15.82 g/L)

一般描述

咖啡因是一种广泛摄入的药理活性物质。它属于甲基黄嘌呤类。[1]它是一种在咖啡、可可和其他植物中发现的天然生物碱。咖啡因可能与骨质疏松症、心血管疾病风险、心律不齐和胃肠道疾病有关。[2]咖啡因可用于治疗体位性低血压、[3]支气管肺发育不良和早产儿呼吸暂停（AOP）。[4]

应用

咖啡因已被用于：
  • 研究其对矮牵牛核荧光的影响[5]
  • 在啮齿动物中作为诱导c-fos表达的刺激物[6]
  • 作为用于牛卵母细胞体外发育的特定培养基中的一种组分[7]

注意

密封保存。

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000419557
    0000419557
    0000419556
    0000419556
    0000407034

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    如果您需要特殊版本，可通过批号或批次号查找具体证书。

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    访问文档库

    Effects of caffeine and chlorogenic acid on propidium iodide accessibility to DNA: consequences on genome size evaluation in coffee tree
    Noirot M, et al.
    Annals of Botany, 92(2), 259-264 (2003)
    A simple method for immunohistochemical staining of zebrafish brain sections for c-fos protein expression
    Chatterjee D, et al.
    Zebrafish, 12(6), 414-420 (2015)
    Orthostatic hypotension in the elderly: diagnosis and treatment
    Gupta V and Lipsitz LA
    The American Journal of Medicine, 120(10), 841-847 (2007)
    L Keskintepe et al.
    Biology of reproduction, 55(2), 333-339 (1996-08-01)
    The objective was to establish an in vitro system in which bovine oocytes can be matured, fertilized, and cultured up to the blastocyst stage without support of serum, BSA, or somatic cells. Media consisted of modified tissue culture medium 199
    Metabolic effects of spices, teas, and caffeine
    Westerterp-Plantenga M, et al.
    Physiology & Behavior, 89(1), 85-91 (2006)
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    实验方案

    Protocol for In-vitro Permeation Testing Using Strat-M® Membranes

    Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

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