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Merck
CN

PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

Synonyms:
PRKAR1
Species:
Human PRKAR1B (5575), Mouse Prkar1b (19085), Rat Prkar1b (25521), Zebrafish prkar1b (767685), Horse PRKAR1B (100054262), cow PRKAR1B (505370), dog PRKAR1B (480805), domestic cat PRKAR1B (101085259), chicken PRKAR1B (416446), domestic guinea pig Prkar1b (100713839)
UniProtKB ID:
P31321, Q8N422
Gene ID:
  • Human(5575) Summary: Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM, Jun 2009]
  • Mouse(19085) protein kinase, cAMP dependent regulatory, type I beta
  • Rat(25521) protein kinase, cAMP dependent regulatory, type I, beta
  • Zebrafish(767685) protein kinase, cAMP-dependent, regulatory, type I, beta
  • Horse(100054262) protein kinase, cAMP-dependent, regulatory, type I, beta
  • cow(505370) protein kinase, cAMP-dependent, regulatory, type I, beta
  • dog(480805) protein kinase, cAMP-dependent, regulatory, type I, beta
  • domestic cat(101085259) protein kinase, cAMP-dependent, regulatory, type I, beta
  • chicken(416446) protein kinase, cAMP-dependent, regulatory, type I, beta
  • domestic guinea pig(100713839) protein kinase, cAMP-dependent, regulatory, type I, beta
  • naked mole-rat(101700715) protein kinase, cAMP-dependent, regulatory, type I, beta

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1406296
Anti-PRKAR1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
HPA026719
Anti-PRKAR1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
C3912
8-(4-Chlorophenylthio)adenosine 3′,5′-cyclic monophosphate sodium salt, ≥97.0% (HPLC), powder,
Species
human
B1427
H-89 dihydrochloride hydrate, ≥98% (HPLC), powder,
Species
human
E1896
Etazolate hydrochloride, solid,
Species
human
I5879
3-Isobutyl-1-methylxanthine, ≥99% (HPLC), powder,
Species
rat, human
M9656
H-8 dihydrochloride, >98% (HPLC),
Species
human, rat

esiRNA

Product Number
Description
Species
EMU014091
MISSION® esiRNA, targeting mouse Prkar1b,
Species
mouse
EHU057261
MISSION® esiRNA, targeting human PRKAR1B,
Species
human