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Merck
CN

BP653

法莫替丁

British Pharmacopoeia (BP) Reference Standard

别名:

N′-(氨基磺酰基)-3-([2-(二氨基亚甲基氨基)-4-噻唑基]甲硫基)丙脒

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About This Item

经验公式(希尔记法):
C8H15N7O2S3
CAS号:
分子量:
337.45
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

Agency

BP

API类

famotidine

形式

solid

保质期

limited shelf life, expiry date on the label

包装

pkg of 100 mg

制造商/商品名称

BP

储存条件

OK to freeze

颜色

white

mp

162-165 °C

溶解性

water: insoluble

应用

pharmaceutical
pharmaceutical small molecule

格式

neat

运输

ambient

储存温度

2-8°C

SMILES字符串

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI key

XUFQPHANEAPEMJ-UHFFFAOYSA-N

基因信息

human ... HRH2(3274)

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一般描述

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Famotidine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Famotidine Tablets
  • 生化/生理作用

    H2组胺受体拮抗剂;抗溃疡剂。

    包装

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他说明

    Sales restrictions may apply.

    WGK

    WGK 2

    闪点(°F)

    Not applicable

    闪点(°C)

    Not applicable


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    分析证书(COA)

    Lot/Batch Number

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    访问文档库

    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 29(1-2), 247-254 (2020)
    Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
    Kelani KM, et al.
    Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
    Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
    Helali N and Monser L
    Journal of Separation Science, 31(2) (2008)
    Capillary zone electrophoresis method for the determination of famotidine and related impurities in pharmaceuticals
    Helali N, et al.
    Talanta, 74(4) (2008)
    Determination of famotidine in acid reduction tablets by HPTLC and videodensitometry of fluorescence quenched zones
    Campbell AN and Sherma J
    Journal of Liquid Chromatography and Related Technologies, 26(16), 2719-2727 (2003)

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