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96708

磷酰基乙酸

Name: 磷酰基乙酸
Brand: SIAL

TraceCERT^®, ³¹P-qNMR Standard, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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About This Item

线性分子式:

(HO)₂P(O)CH₂CO₂H

CAS号:

4408-78-0

分子量:

140.03

EC 号:

224-558-1

MDL编号:

MFCD00004311

UNSPSC代码:

41116107

PubChem化学物质编号:

329770527

NACRES:

NA.24

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质量水平

300

产品线

TraceCERT^®

等级

TraceCERT^®

表单

solid

保质期

limited shelf life, expiry date on the label

制造商/商品名称

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

技术

qNMR: suitable

mp

143-146 °C (lit.)

应用

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical

SMILES字符串

OC(=O)CP(O)(O)=O

InChI

1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7)

InChI key

XUYJLQHKOGNDPB-UHFFFAOYSA-N

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一般描述

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out our entire range of quantitative NMR standards (qNMR standards)

应用

Enhancing Guide RNA Stability and Editing Yields: Phosphonoacetate modifications have been shown to significantly enhance the stability and editing efficiency of guide RNAs for Cas9-based genome editors. This development has profound implications in genetic engineering and therapeutic applications, where precision and stability are crucial (Ryan et al., 2023).

Glomerular and Tubulointerstitial Nephropathy Study: Phosphonoacetic acid has been indirectly related to studies on kidney diseases such as glomerular and tubulointerstitial nephropathy, showcasing its potential relevance in medical research to understand and treat complex renal conditions (Pleško et al., 2021).

Environmental Impact of Phosphonoacetate: Research on PMIDA-modified magnetic nanoparticles, including those related to phosphonoacetate, explores their application in liver MRI, indicating its utility in enhancing diagnostic imaging techniques and its potential environmental implications (Demin et al., 2018).

CRISPR-Cas Specificity Improvement: Modifications including phosphonoacetate derivatives have been employed to improve the specificity and efficiency of CRISPR-Cas systems in gene editing, underscoring the chemical′s role in cutting-edge biotechnological research (Ryan et al., 2018).

Cardiovascular Pharmacology: Studies involving phosphonoacetic acid have been connected to cardiovascular pharmacology, particularly in exploring the mechanisms that inhibit calcification in vascular tissues, which is vital for developing treatments for vascular calcification diseases (Duan et al., 2017).

法律信息

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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磷酰基乙酸