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Merck
CN

933856

Sigma-Aldrich

γ-缬草内酯

greener alternative

BioRenewable, anhydrous, DMF and NMP substitute, ≥99%

别名:

γ-甲基-γ-丁内酯, 4,5-二氢-5-甲基-2(3H)-呋喃酮, 4-羟基正戊酸内酯, γ-甲基-γ-丁内酯

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About This Item

经验公式(希尔记法):
C5H8O2
CAS号:
分子量:
100.12
Beilstein:
80420
MDL编号:
UNSPSC代码:
12352100
NACRES:
NA.21

蒸汽密度

3.45 (vs air)

质量水平

检测方案

≥99%

形式

liquid

环保替代产品特性

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

杂质

≤50 ppm water

颜色

colorless to light yellow

折射率

n20/D 1.432 (lit.)

bp

207-208 °C (lit.)
82-85 °C/10 mmHg (lit.)

mp

−31 °C (lit.)

密度

1.05 g/mL at 25 °C (lit.)

环保替代产品分类

SMILES字符串

CC1CCC(=O)O1

InChI

1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3

InChI key

GAEKPEKOJKCEMS-UHFFFAOYSA-N

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一般描述

We are committed to providing environmentally friendly products, and γ-Valerolactone (GVL) is a prime example of our dedication to this effort. GVL is a bio-based solvent derived from renewable sources, which makes it a sustainable alternative to traditional organic solvents like NMP and DMF. GVL aligns with the principles of "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries" and offers exceptional solubility properties. As a result, it is an effective solvent for various applications, such as chemical synthesis. GVL is non-toxic, non-irritating, and biodegradable, making it a safe and eco-friendly choice for both consumers and the environment. Overall, γ-Valerolactone is an excellent option for companies and researchers seeking to reduce their environmental footprint while still delivering high-quality products.

应用

  • Peptide synthesis
  • Cross-coupling reactions
  • Nonaqueous redox-flow batteries
  • Polymerization reaction
  • Extraction

特点和优势

  • Bio-based
  • Made from Renewable Resource - rice
  • Biodegradable
  • Non-toxic
  • Low vapor pressure

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

闪点(°F)

204.8 °F

闪点(°C)

96 °C


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分析证书(COA)

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γ-Valerolactone as an alternative biomass-derived medium for the Sonogashira reaction
Green Chemistry, 17, 1071-1076 (2015)
Nonaqueous redox-flow batteries: organic solvents, supporting electrolytes, and redox pairs
Ke Gong, Qianrong Fang, Shuang Gu, Sam Fong Yau Li and Yushan Yan
Energy & Environmental Science, 8, 3515-3530 (2015)
Green solid-phase peptide synthesis 4. γ-Valerolactone and N-formylmorpholine as green solvents for solid phase peptide synthesis
Kumar A, et al.
Tetrahedron Letters, 58, 2986-2988 (2017)
γ-Valerolactone as a Green Solvent for Extracting Carboxylic Acids and Alcohols from n-Tetradecane: Equilibrium Data for Model Systems at 298.15 K
Carlos E. S. Dantas and Roberta Ceriani
Journal of Chemical and Engineering Data, Volume 67, Issue 6, 1460?1473-1460?1473 (2022)
γ-Valerolactone (GVL): An eco-friendly anchoring solvent for solid-phase peptide synthesis
Musaimi O A, et al.
Tetrahedron Letters, 60, 151058-151058 (2019)

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