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Merck
CN

920193

Sigma-Aldrich

Cyrene 2-Methyltetrahydrofuran Blend

greener alternative

BioRenewable, DMF and NMP Substitute

别名:

2-MeTHF Solution, 2-Methyltetrahydrofuran solution, Cyrene solution

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About This Item

经验公式(希尔记法):
C6H8O3
分子量:
128.13
UNSPSC代码:
12352212
NACRES:
NA.07

形式

liquid

包含

30-80 ppm BHT as stabilizer

环保替代产品特性

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

renewable carbon content

100%

密度

1.153 g/mL

环保替代产品分类

一般描述

Cyrene 2-Methyltetrahydrofuran Blend with BHT as an inhibitor is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.

This Cyrene blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene nor 2-Methyltetrahydrofuran have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.

This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is BioRenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.

应用

This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:

特点和优势

  • Independently certified as 100% renewable carbon.
  • Closer physical properties of NMP and DMF while maintaining high reaction yields.
  • Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
  • Both Cyrene and 2-MeTHF are also much safer for handling without the genotoxic concerns of other solvents.
  • It has a lower viscosity than neat Cyrene making it more optimized for automated processes.

法律信息

CYRENE is a trademark of Circa Group Pvt Ltd

象形图

FlameCorrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2

补充剂危害

WGK

WGK 2

法规信息

危险化学品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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  1. What is a BioRenewable solvent?

    BioRenewable solvents are sourced from renewable and sustainable biobased materials, such as soy/palm oil, wood waste, hay or corn byproducts, etc. It is important to highlight that our BioRenewable products do not compete with food production.

  2. Why should you use BioRenewable solvents?

    You will contribute to create a sustainable world, significantly lowering environmental impact. Biorenewable solvents also decrease petroleum sources dependency, have higher recovery rates, and/or are safer for handling and disposal.

  3. Do BioRenewable solvents have a similar quality to petroleum-based solvents?

    BioRenewable solvents can have the same or higher purity level compared to traditional solvents. These solvents are free of the many byproducts of petroleum manufacturing, such as benzene, aldehydes, and ethers.

Improved 2-pyridyl reductive homocoupling reaction using biorenewable solvent Cyrene?(dihydrolevoglucosenone)
Webb DA, et al.
RSC Sustainability, 1, 1522-1529 (2023)
Cyrene? blends: a greener solvent system for organic syntheses
Sullivan C, et al.
Green Chemistry, 24, 7184-7193 (2022)

相关内容

Why should you have to choose between solvents that are ecological and those that are reliable? Enjoy both at once with our biorenewable and greener solutions. Cyrene™ solvent is a new dipolar aprotic alternative to common REACH restricted solvents, such as N methyl-2-pyrrolidone (NMP) and Dimethylformamide (DMF).

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