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一般描述
聚乙二醇(PEG)是多功效的非离子型聚合物，低毒性、疏水性和半晶体结构令其广泛用于工业和药物领域。PEG由重复的CH2-CH2O单元组成，即使在高温条件下也能溶于单体和水相，在各种研究中发挥重要作用。
应用
- 新型纤维状银（NP）装饰的粘土聚合物复合材料：对于受到主要微污染物和细菌污染水净化的影响：该研究展示了聚乙二醇（PEG）在新型纤维状粘土聚合物复合材料中的应用，提高了水处理系统中微污染物和细菌的去除效率（Goswami et al., 2024）。
- 追求均匀性：关于实现均匀聚乙二醇的进展和挑战的综述: 该论文综述了聚乙二醇（PEG）均匀生产（uniform production）的进展，这对其在药物递送和药物制剂中的应用至关重要，该论文讨论了材料的溶解度、生物相容性和稳定特性（Bento et al., 2024）。
- 评估了负载阿托伐他汀钙的聚乙二醇-聚L-乳酸纳米颗粒的结构稳定性和药物封装效率：: 该研究评估了聚乙二醇在聚合物纳米颗粒中的用途，重点关注了药物封装效率和稳定性的优化，这对有效的药物递送系统至关重要（Feng et al., 2024）。
- 对表观遗传酶具有程序响应性的纳米材料的设计与评价: 该研究探讨了聚乙二醇在针对表观遗传酶的响应性纳米材料设计中的作用，展示了聚乙二醇在增强药物应用方面的多功能性（Ray et al., 2024）。
- 用于敷料应用的由聚乳酸/聚乙二醇和木麒麟（Pereskia aculeata Miller）提取物组成的膜: 该论文重点介绍了聚乙二醇在生物相容性的高效伤口敷料材料开发中的应用，将聚乳酸和天然提取物结合起来可促进愈合过程 （Mendes et al., 2024）。
生化/生理作用
聚乙二醇（PEG或macrogol）广泛用作化妆品和药品中的添加剂。添加这种亲水性聚合物后，可体外阻断和逆转某些表面活性剂的失活。PEG及其衍生物或改性物可用作乳液聚合的大分子引发剂、稳定剂、分散剂。
特点和优势
- 环境优化型
- 生物相容性
- 独特的溶剂
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
281.5 °F - closed cup
闪点(°C)
138.6 °C - closed cup
个人防护装备
Eyeshields, Gloves, type N95 (US)
Polymer nanocomposites for biomedical applications
Rahmani S, et al.
Journal of Separation Science, 175-215 (2022)
Polyethylene glycol/surfactant mixtures improve lung function after HCl and endotoxin lung injuries.
K W Lu et al.
American journal of respiratory and critical care medicine, 164(8 Pt 1), 1531-1536 (2001-11-13)
Addition of nonionic polymers such as polyethylene glycol (PEG) and dextran ameliorates inactivation of Survanta by a variety of substances in vitro. Addition of polymers to Survanta also improves pulmonary function when used to treat rats with lung injury caused
Yiming Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 29(9), 3024-3033 (2013-02-26)
Through zeta potential and surface tension measurements and a series of polymerization experiments, the role of poly(ethylene glycol) (PEG) in the process of surfactant-free polymerization of styrene (St)/methyl methacrylate (MMA) has been investigated experimentally. Nanoscale and stable copolymer particles were
Katharina Wylon et al.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 12, 67-67 (2016-12-22)
Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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