一般描述
聚乙二醇(PEG)是多功效的非离子型聚合物，低毒性、疏水性和半晶体结构令其广泛用于工业和药物领域。PEG由重复的CH2-CH2O单元组成，即使在高温条件下也能溶于单体和水相，在各种研究中发挥重要作用。
应用
- Novel fibrous Ag(NP) decorated clay-polymer composite: Implications in water purification contaminated with predominant micro-pollutants and bacteria: This study demonstrates the use of poly(ethylene glycol) (PEG) for the creation of novel fibrous clay-polymer composites, enhancing the removal efficiency of micro-pollutants and bacteria in water treatment systems (Goswami et al., 2024).
- Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol: This review addresses the advances in the uniform production of poly(ethylene glycol) (PEG), critical for its application in drug delivery and pharmaceutical formulations, discussing the material′s solubility, biocompatibility, and stabilization properties (Bento et al., 2024).
- Assessing the structural stability and drug encapsulation efficiency of poly(ethylene glycol)-poly(L-lactic acid) nanoparticles loaded with atorvastatin calcium: The study evaluates the use of PEG in polymeric nanoparticles, focusing on optimizing drug encapsulation efficiency and stability, which is pivotal for effective drug delivery systems (Feng et al., 2024).
- Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes: This research explores the role of PEG in designing responsive nanoscale materials aimed at targeting epigenetic enzymes, showcasing PEG′s versatility in enhancing pharmaceutical applications (Ray et al., 2024).
- Membranes composed of poly(lactic acid)/poly(ethylene glycol) and Ora-pro-nóbis (Pereskia aculeata Miller) extract for dressing applications: This article highlights the application of PEG in developing biocompatible and efficient wound dressing materials, combining poly(lactic acid) and natural extracts to enhance healing processes (Mendes et al., 2024).
生化/生理作用
聚乙二醇（PEG或macrogol）广泛用作化妆品和药品中的添加剂。添加这种亲水性聚合物后，可体外阻断和逆转某些表面活性剂的失活。PEG及其衍生物或改性物可用作乳液聚合的大分子引发剂、稳定剂、分散剂。
特点和优势
- 环境优化型
- 生物相容性
- 独特的溶剂
WGK
WGK 1
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Eyeshields, Gloves, type N95 (US)
Polymer nanocomposites for biomedical applications
Rahmani S, et al.
Journal of Separation Science, 175-215 (2022)
Yiming Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 29(9), 3024-3033 (2013-02-26)
Through zeta potential and surface tension measurements and a series of polymerization experiments, the role of poly(ethylene glycol) (PEG) in the process of surfactant-free polymerization of styrene (St)/methyl methacrylate (MMA) has been investigated experimentally. Nanoscale and stable copolymer particles were
Polyethylene glycol/surfactant mixtures improve lung function after HCl and endotoxin lung injuries.
K W Lu et al.
American journal of respiratory and critical care medicine, 164(8 Pt 1), 1531-1536 (2001-11-13)
Addition of nonionic polymers such as polyethylene glycol (PEG) and dextran ameliorates inactivation of Survanta by a variety of substances in vitro. Addition of polymers to Survanta also improves pulmonary function when used to treat rats with lung injury caused
Katharina Wylon et al.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 12, 67-67 (2016-12-22)
Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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