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安全信息

CHGE72HS3

Millipore

Millipore Express® SHC High Area, Cartridge

cartridge nominal length 20 in. (50 cm), filter diam. 2.7 in. (6.9 cm), Code 7

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UNSPSC代码:
23151806

物料

polypropylene support
silicone seal

质量水平

400

管理合规性

meets FDA 21 CFR 177-182 (all component materials)

无菌性

non-sterile

灭菌适用性

autoclavable compatible
steam-in-place compatible

产品线

EMPROVE® Filter
Millipore Express®

特点

hydrophilic

制造商/商品名称

Millipore Express®

参数

≤112.8 mL/min air diffusion at 2.75 bar (40 psig) (in water)
1700 mbar max. differential pressure (25 psi) at 80 °C (Forward)
1700 mbar max. inlet pressure (25 psi) at 80 °C (Forward)
2100 mbar max. inlet pressure (30 psi) at 25 °C (Reverse)
340 mbar max. differential pressure (5 psi) at 135 °C (Forward)
340 mbar max. inlet pressure (5 psi) at 135 °C (Forward)
69 mbar max. inlet pressure (1 psi) at 135 °C (Reverse)
6900 mbar max. differential pressure (100 psi) at 25 °C (Forward)
6900 mbar max. inlet pressure (100 psi) at 25 °C (Forward)

技术

sterile filtration: suitable

长度

20 in.

宽度

2.8 in.

纯化柱标称长度

20 in. (50 cm)

过滤器直径

2.7 in. (6.9 cm)

filter filtration area

2.0 m2

过滤器尺寸

20 in.

杂质

≤0.25 EU/mL bacterial endotoxins (LAL test, aqueous extraction)
<0.25 EU/mL USP bacterial endotoxins (LAL test, sample aqueous extraction)

基质

Millipore Express® SHC High Area

pore size

0.5/0.2 μm pore size

泡点

≥4000 mbar (58 psig), air with water

柱代码

Code 7

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相关类别

一般描述

Millipore Express® SHC filters have an on-board polyethersulfone membrane prefilter which protects the 0.2 μm membrane from premature plugging and extends filtration capacity, so you get sterilizing-grade performance with superior throughput. The CHGE72HS3 cartridge filter features a 0.5/0.2 μm pore size, a filtration area of 0 and a Code 7 cartridge configuration.

Millipore Express® SHC filters provide you with a single solution for a range of process fluids, minimizing validation efforts and simplifying filter inventory and stocking requirements. With Millipore Express® SHC filters, you increase productivity, shorten cycle-time and reduce cost.

应用

  • Media additives
  • Column protection
  • Concentrated protein streams
  • Cell harvest (post clarification)
  • Caustics/pH adjusters
  • Buffers
  • CIP solution

特点和优势

  • High capacity, high flux hydrophilic PES membranes
  • Validated sterilizing-grade performance
  • Easy wetting and integrity testing
  • Superior throughput in high fouling streams, including media and protein containing solutions
  • Increased capacity for improved process efficiency and economy
  • Broad chemical compatibility across a wide pH range (1-14) — caustic compatible

包装

Double Easy-Open bag

制备说明

Sterilization Method: 5 autoclave cycles of 60 min at 126 °C or 5 forward SIP cycles of 30 min at 135 °C

This product was manufactured with a MILLIPORE EXPRESS® membrane which meets the criteria for a "non-fiber releasing" filter as defined in 21 CFR 210.3 (b) (6).

分析说明

After sterilization and a controlled water flush of 40 L, samples exhibited <500 ppb TOC per USP 643 and <1.3 μS/cm per USP 645 at 25 °C.

Bacterial Retention: Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 107 CFU/cm2 using ASTM® F838 methodology.

其他说明

Directions for Use
  • Organism Retention: Microorganism
  • Mode of Action: Filtration (size exclusion)
  • Application: BioProcessing
  • Intended Use: Reduction or removal of microorganism/bioburden
  • Instructions for Use: Please refer wetting instructions of Filters with MILLIPORE EXPRESS® Membrane user guide
  • Storage Statement: Please refer Filters with MILLIPORE EXPRESS® Membrane user guide
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.

法律信息

ASTM is a registered trademark of American Society for Testing and Materials
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
MILLIPORE EXPRESS is a registered trademark of Merck KGaA, Darmstadt, Germany

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