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Merck
CN

108693

SAFC

Deviron® C16

greener alternative

Detergent 30% solution, EMPROVE® EVOLVE

制药生产

别名:

Deviron® C16 Detergent EMPROVE® EVOLVE solution, N,N-Dimethylmyristylamine N-oxide

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About This Item

线性分子式:
CH3(CH2)13N(O)(CH3)2
CAS号:
分子量:
257.46
Beilstein:
4245192
MDL编号:
UNSPSC代码:
12161902

质量水平

产品线

EMPROVE® EVOLVE

表单

liquid

环保替代产品特性

Designing Safer Chemicals
Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

应用

pharma/biopharma processes

环保替代产品分类

储存温度

15-25°C

SMILES字符串

[N](=O)(CCCCCCCCCCCCCC)(C)C

InChI

1S/C16H35NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17(2,3)18/h4-16H2,1-3H3

InChI key

ONHFWHCMZAJCFB-UHFFFAOYSA-N

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一般描述

Detergents, such as non-ionic surfactants, are used in biomanufacturing processes for a variety of applications including viral inactivation and cell lysis. Detergent-mediated viral inactivation is widely used in multiple biotherapeutic production processes to ensure meeting regulatory requirements for viral safety.

Our SAFC portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC portfolio of high-quality products withstands strict quality control procedures.

应用

REACH compliantdetergent used in viral inactivation or cell lysis.

法律信息

DEVIRON is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

212.0 °F

闪点(°C)

> 100 °C

法规信息

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商品

本文介绍了细胞裂解的主要考虑因素,以及如何通过高盐浓度配合耐高盐核酸内切酶提高AAV载体生产工艺的病毒滴度和感染能力。

This page describes key considerations for cell lysis and how the combination of a high salt concentration and a salt tolerant endonuclease can be used to increase vector titer and infectivity during AAV vector manufacturing.

相关内容

The use of Benzonase® endonuclease can significantly reduce the levels of DNA by more than 100,000-fold while also reducing viscosity and protecting downstream equipment from DNA fouling. However, optimization strategies and DoE are critical when it comes to reducing DNA in your process. Setting up a DoE for your Benzonase® endonuclease application can help you find the optimal operation conditions that deliver the required DNA clearance from your process.

Learn more on mAb downstream processing, more specifically virus inactivation and the relevant associated products.

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