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Merck
CN

108693

SAFC

Deviron® C16

greener alternative

Detergent 30% solution, EMPROVE® EVOLVE

Pharma Manufacturing

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别名:
Deviron® C16 Detergent EMPROVE® EVOLVE solution, N,N-Dimethylmyristylamine N-oxide
线性分子式:
CH3(CH2)13N(O)(CH3)2
CAS号:
分子量:
257.46
Beilstein:
4245192
UNSPSC代码:
12161902

质量水平

产品线

EMPROVE® EVOLVE

形式

liquid

环保替代产品特性

Designing Safer Chemicals
Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

应用

pharma/biopharma processes

环保替代产品分类

储存温度

15-25°C

InChI

1S/C16H35NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17(2,3)18/h4-16H2,1-3H3

InChI key

ONHFWHCMZAJCFB-UHFFFAOYSA-N

一般描述

Detergents, such as non-ionic surfactants, are used in biomanufacturing processes for a variety of applications including viral inactivation and cell lysis. Detergent-mediated viral inactivation is widely used in multiple biotherapeutic production processes to ensure meeting regulatory requirements for viral safety.

Our SAFC portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC portfolio of high-quality products withstands strict quality control procedures.

应用

REACH compliantdetergent used in viral inactivation or cell lysis.

法律信息

DEVIRON is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

212.0 °F

闪点(°C)

> 100 °C

法规信息

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商品

本文介绍了细胞裂解的主要考虑因素,以及如何通过高盐浓度配合耐高盐核酸内切酶提高AAV载体生产工艺的病毒滴度和感染能力。

This page describes key considerations for cell lysis and how the combination of a high salt concentration and a salt tolerant endonuclease can be used to increase vector titer and infectivity during AAV vector manufacturing.

相关内容

The use of Benzonase® endonuclease can significantly reduce the levels of DNA by more than 100,000-fold while also reducing viscosity and protecting downstream equipment from DNA fouling. However, optimization strategies and DoE are critical when it comes to reducing DNA in your process. Setting up a DoE for your Benzonase® endonuclease application can help you find the optimal operation conditions that deliver the required DNA clearance from your process.

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