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Merck
CN

1.02144

SAFC

磷酸氢钙

anhydrous, fine powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, FCC, E 341(ii)

Pharma Manufacturing

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别名:
Calcium hydrogen phosphate, Calcium orthophosphate, Calcium phosphate dibasic
经验公式(希尔记法):
HCaO4P
CAS号:
分子量:
136.06
MDL编号:
UNSPSC代码:
12352302
E编号:
E341 (ii)
EC索引号:
231-826-1

Agency

BP
Ph. Eur.
USP

质量水平

管理合规性

FCC

产品线

EMPROVE® ESSENTIAL

形式

fine powder

效能

10000 mg/kg LD50, oral (Rat)
>7940 mg/kg LD50, skin (Rabbit)

粒径

(see specification)

pH值(酸碱度)

7 (20 °C, 10 g/L in H2O, suspension)

mp

370 °C (decomposition)

密度

2.89 g/cm3 at 20 °C

应用

pharmaceutical
semi-solid formulation
solid formulation

储存温度

2-30°C

InChI

1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

InChI key

FUFJGUQYACFECW-UHFFFAOYSA-L

一般描述

To address challenges of solid formulation manufacturing, we have developed a comprehensive product portfolio to meet with your solid dosage needs in mind. Although solid dose formulations are one of the the most established dosage forms in the pharmaceutical market, the complexity of manufacturing final drug products is becoming more and more challenging. API stability, release kinetics and bioavailability limitations, such as low API solubility, are just a few of many critical obstacles on the way to the market.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Calcium hydrogen phosphate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, calcium hydrogen phosphate is primarily used as a filler/binder.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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