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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
6F-H2, monoclonal
Application:
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
human
Citations:
25
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-WT1抗体,克隆6F-H2, clone 6F-H2, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6F-H2, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... WT1(7490)
Analysis Note
已通过免疫印迹对Jurkat和Raji细胞的RIPA裂解液进行常规评估
Application
抗-WT1抗体(克隆6F-H2)是一种用于检测WT1(又称维尔姆斯瘤)的小鼠单克隆抗体,目前已通过WB、ICC & IHC应用验证。
Biochem/physiol Actions
WT1
General description
55-60kDa
Immunogen
6His标记融合蛋白,对应人WT1(维尔姆斯瘤)的1-181位残基。
Physical form
形式:纯化
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Chen Wu et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 8(9), 1163-1169 (2013-08-16)
The Wilms' tumor gene (WT1) has been identified as an oncogene in many malignant diseases, and aberrant WT1 expression has been linked to development, progression, and prognosis of non-small-cell lung cancer (NSCLC). We sought to investigate the underlying mechanism of
Kazunori Inoue et al.
The Journal of clinical investigation, 129(3), 1295-1313 (2019-02-19)
We identified 2 genes, histone deacetylase 1 (HDAC1) and HDAC2, contributing to the pathogenesis of proteinuric kidney diseases, the leading cause of end-stage kidney disease. mRNA expression profiling from proteinuric mouse glomeruli was linked to Connectivity Map databases, identifying HDAC1
Caihua Xu et al.
PloS one, 8(8), e68837-e68837 (2013-08-13)
The Wilms' tumor suppressor gene (WT1) has been identified as an oncogene in many malignant diseases such as leukaemia, breast cancer, mesothelioma and lung cancer. However, the role of WT1 in non-small-cell lung cancer (NSCLC) carcinogenesis remains unclear. In this
Rebecca Vicente-Steijn et al.
PloS one, 10(9), e0136025-e0136025 (2015-09-22)
Morphological and functional differences of the right and left ventricle are apparent in the adult human heart. A differential contribution of cardiac fibroblasts and smooth muscle cells (populations of epicardium-derived cells) to each ventricle may account for part of the
Jing Zhou et al.
Biology open, 7(5) (2018-04-19)
Mesodermal populations can be generated in vitro from mouse embryonic stem cells (mESCs) using three-dimensional (3-D) aggregates called embryoid bodies or two-dimensional (2-D) monolayer culture systems. Here, we investigated whether Brachyury-expressing mesodermal cells generated using 3-D or 2-D culture systems
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