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732613

Sigma-Aldrich

聚乙二醇甲基醚

average MN 20,000, methoxy, hydroxyl

别名:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

线性分子式:
CH3(OCH2CH2)nOH
CAS号:
9004-74-4
MDL编号:
MFCD00084416
UNSPSC代码:
12162002
NACRES:
NA.23

产品名称

聚乙二醇甲基醚, average Mn 20,000

蒸汽密度

>1 (vs air)

质量水平

100

蒸汽压

0.05 mmHg ( 20 °C)

表单

powder or crystals

分子量

average Mn 20,000

mp

64-69 °C

Mw/Mn

≤1.2

Ω端

hydroxyl

α端

methoxy

储存温度

−20°C

SMILES字符串

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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应用

  • Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C.：开发脱氧胆酸接枝的PEG化壳聚糖胶束用于有效递送丝裂霉素C，说明PEG化物质在药物制剂和药物传输系统中的应用前景(Zhang et al., 2015)。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

359.6 °F

闪点(°C)

182 °C

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分析证书(COA)

Lot/Batch Number
MKCQ4514
MKCM1673
MKCL2175
MKCK9517
MKCH9258

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Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
Hyo Won Seo et al.
Biomaterials, 34(11), 2748-2757 (2013-01-25)
The effectiveness of systemically administered anticancer treatments is limited by difficulties in achieving therapeutic doses within tumors, a problem that is complicated by dose-limiting side effects to normal tissue. To increase the efficacy and reduce the toxicity of systemically administered
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
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