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Merck
CN

729108

Sigma-Aldrich

聚乙二醇甲醚巯基

average MN 800, chemical modification reagent thiol reactive, methoxy, thiol

别名:

PEG 硫醇, mPEG 硫醇, 甲氧基 PEG 硫醇, 甲氧基聚乙二醇硫醇

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About This Item

线性分子式:
CH3O(CH2CH2O)nCH2CH2SH
UNSPSC代码:
12162002
NACRES:
NA.23

product name

聚乙二醇甲醚巯基, average Mn 800

形式

solid

质量水平

分子量

average Mn 800

反应适用性

reagent type: chemical modification reagent
reactivity: thiol reactive

杂质

≤10% disulfide

转变温度

Tm 32-37 °C

Mw/Mn

≤1.1

Ω端

thiol

α端

methoxy

聚合物结构设计

shape: linear
functionality: monofunctional

储存温度

2-8°C

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应用

聚乙二醇单甲醚硫醇可用于 功能化修饰 Fe3O4@Au 核壳纳米颗粒。硫醇化的PEG提高水溶性 并显著降低纳米毒性。

它可作为前体合成用于基因治疗的PEG偶联 聚β氨基酯)复合物。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3


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Nisha C. Kalarickal, Stephen Rimmer, Prodip Sarker, and Jean-Christophe Leroux
Macromolecules, 40, 1874-1874 (2007)
Cristina Gentilini, Mariangela Boccalon, and Lucia Pasquato
The Journal of Organic Chemistry, 3308-3308 (2008)

商品

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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