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Merck
CN

717142

Sigma-Aldrich

聚乙二醇(PEG)二硫

average Mn 1,000, thiol

别名:

聚乙二醇二硫醇

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About This Item

线性分子式:
HSCH2CH2(OCH2CH2)nSH
UNSPSC代码:
12162002
NACRES:
NA.23

product name

聚乙二醇(PEG)二硫, average Mn 1,000

形式

solid

质量水平

分子量

average Mn 1,000

反应适用性

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

29-33 °C

Ω端

thiol

α端

thiol

聚合物结构设计

shape: linear
functionality: homobifunctional

储存温度

2-8°C

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应用

硫醇官能化的纳米颗粒可用于粘膜粘附药物递送,合成二硫醇封端的两亲性二嵌段共聚物,双配位基二硫醇-聚(乙二醇)-聚(d,l-丙交酯)(SH2-PEG-PDLLA)。通过简单的配体交换,金纳米颗粒可以很容易地用PEG二硫醇官能化。

其他说明

分子量:Mn为900-1,100

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Jian Yang et al.
Biomacromolecules, 15(4), 1346-1354 (2014-03-13)
Thiol-modified nanoparticles have potential applications in mucoadhesive drug delivery and have been examined in this regard for topical ocular delivery. In this paper we provide a simple method for the synthesis of a dithiol terminated amphiphilic diblock copolymer. Bidentate dithiol-poly(ethylene
Nadeau J
Introduction to Experimental Biophysics: Biological Methods for Physical Scientists null
Qiang Wei et al.
ACS biomaterials science & engineering, 6(8), 4687-4701 (2021-01-19)
Hydrogels have been widely explored for the delivery of cells in a variety of regenerative medicine applications due to their ability to mimic both the biochemical and physical cues of cell microniches. For bone regeneration, in particular, stiff hydrogels mimicking

商品

将基于水凝胶的生物材料用于递送和募集细胞以促进体内组织再生是新生的研究热题。本文讨论了水凝胶在细胞递送和组织再生中的应用。

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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