202509
聚乙二醇甲基醚
average Mn 2,000, methoxy, hydroxyl
别名:
mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚
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关于此项目
线性分子式:
CH3(OCH2CH2)nOH
化学文摘社编号:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
产品名称
聚乙二醇甲基醚, average Mn ~2,000
SMILES string
O(CCO)C
InChI
1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
InChI key
XNWFRZJHXBZDAG-UHFFFAOYSA-N
vapor density
>1 (vs air)
vapor pressure
0.05 mmHg ( 20 °C)
form
flakes (or pellets)
mol wt
average Mn ~2,000
viscosity
54.6 cSt(210 °F)(lit.)
transition temp
Tm 52 °C
functional group
hydroxyl
Quality Level
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Application
插入聚（乙二醇）甲基醚结合的树状聚合物可作为抗癌药物的载体。这种新型药物载体具有生物相容性表面和药物的内部封装。
它可作为一种成孔剂，以制备用于去除大分子的超滤膜。
还可将其作为起始材料，用于制备生物可降解的聚（L-丙氨酸）与mPEG的两亲性共聚物。
它可作为一种成孔剂，以制备用于去除大分子的超滤膜。
还可将其作为起始材料，用于制备生物可降解的聚（L-丙氨酸）与mPEG的两亲性共聚物。
Features and Benefits
插入聚（乙二醇）甲基醚(mPEG)侧链可增强聚合物基质的亲水性和柔韧性。
General description
它是聚乙二醇（PEG）大分子单体，具有由甲基醚组成的反应性链端。PEG链末端的醚化可以通过在碱性条件下使其与烷基卤化物进行反应来实现。mPEG可以进行交联以形成水凝胶;聚合反应可以通过氧化还原反应或自由基引发剂进行引发。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
359.6 °F - closed cup
flash_point_c
182 °C - closed cup
ppe
Eyeshields, Gloves
Yi Wei et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13984-13992 (2012-09-04)
The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Junming Li et al.
Journal of biomedical nanotechnology, 8(5), 809-817 (2012-08-15)
In this study, quercetin (QC) with cancer chemoprevention effect and anticancer potential was loaded into polymeric micelles of methoxy poly(ethylene glycol)-cholesterol conjugate (mPEG-Chol) in order to increase its water solubility. MPEG-Chol with lower critical micelle concentration (CMC) value (4.0 x
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
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