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Merck
CN

182028

Poly(ethylene glycol)

greener alternative

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

别名:

PEO

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关于此项目

线性分子式:
(-CH2CH2O-)n
化学文摘社编号:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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产品名称

聚环氧乙烷, average Mv 600,000 (nominal), powder

SMILES string

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

form

powder

mol wt

average Mv 600,000 (nominal)

contains

200-500 ppm BHT as inhibitor

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

viscosity

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

transition temp

Tm 65 °C

Ω-end

hydroxyl

α-end

hydroxyl

application(s)

battery manufacturing

greener alternative category

Quality Level

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Application

聚环氧乙烷可用于制备:
  • 用于药物缓释的可生物吸收、可注射水凝胶。
  • 用于燃料电池的PEO/氧化石墨烯复合电极膜。
  • 聚环氧乙烷-b-聚ε-己内酯(PEO-b-PC)二嵌段共聚物。内含氯沙坦钾的(PEO-b-PCL)共聚物可用作药物载体。

General description

聚环氧乙烷(PEO)2是一种高分子量、非离子水溶性聚合物。它在水化时形成凝胶,并具有良好的膨胀能力。EPO聚合物无毒,广泛用于药物递送系统以改善药物可溶性。
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jun Li et al.
Journal of biomedical materials research. Part A, 65(2), 196-202 (2003-05-08)
Polymeric hydrogels long have attracted interest for biomaterials applications because of their generally favorable biocompatibility. High in water content, they are particularly attractive for delivery of delicate bioactive agents, such as proteins. However, because they require covalent crosslinking for gelation
Angeliki Chroni et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-24)
We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers were prepared by organic solvent evaporation method
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in

商品

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Discover hydrogels, biocompatible materials for drug delivery, tissue engineering, wound care, and 3D bioprinting in innovative biomedical applications

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