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Merck
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MTOR

mechanistic target of rapamycin (serine/threonine kinase)

别名:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
物种:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), cow MTOR (100139219), Horse MTOR (100051341), Goat MTOR (100860902), dog MTOR (478232), sheep MTOR (100271659), domestic guinea pig Mtor (100724938), chicken MTOR (419455) ...展开
UniProtKB ID:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
基因ID:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

货号
说明
物种反应性
应用
OP97
Anti-mTOR/FRAP (Ab-2) Mouse mAb (22C2), liquid, clone 22C2, Calbiochem®,
物种反应性
human
应用
SAB4504476
抗 磷酸化-mTOR (pSer 2448 ) 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
09-213
抗磷酸化mTOR（Ser2448）抗体, Upstate®, from rabbit,
物种反应性
human
应用
western blot
05-1592
抗-mTOR抗体，克隆21D8.2, clone 2ID8.2, from mouse,
物种反应性
human, mouse
应用
immunocytochemistry
western blot
SAB4301526
Anti-phospho-mTOR (pSer2481) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
SML0120
哌克昔林 马来酸盐, ≥98% (HPLC),
物种
human
PZ0235
PF-04691502, ≥98% (HPLC),
物种
human

Proteins

货号
说明
物种
14-770-M
mTOR（1362端）蛋白，活性，10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
物种
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EHU101641
MISSION® esiRNA, targeting human MTOR,
物种
human