ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
别名:
SRK, STCD, STD, TZK, ZAP-70
物种:
Human ZAP70 (7535), Mouse Zap70 (22637), Rat Zap70 (301348), dog ZAP70 (100271860), domestic cat ZAP70 (101097059), chicken ZAP70 (420086), Zebrafish zap70 (553615), sheep ZAP70 (101112639), Domestic Rabbit ZAP70 (100342021), naked mole-rat Zap70 (101716577) ...展开
UniProtKB ID:
基因ID:
- Human(7535) Summary: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(22637) zeta-chain (TCR) associated protein kinase
- Rat(301348) zeta-chain (TCR) associated protein kinase 70
- dog(100271860) zeta-chain (TCR) associated protein kinase 70kDa
- domestic cat(101097059) zeta-chain (TCR) associated protein kinase 70kDa
- chicken(420086) zeta-chain (TCR) associated protein kinase 70kDa
- Zebrafish(553615) zeta-chain (TCR) associated protein kinase
- sheep(101112639) zeta-chain (TCR) associated protein kinase 70kDa
- Domestic Rabbit(100342021) zeta-chain (TCR) associated protein kinase 70kDa
- naked mole-rat(101716577) zeta-chain (TCR) associated protein kinase 70kDa
- domestic guinea pig(100713473) zeta-chain (TCR) associated protein kinase 70kDa
- cow(504509) zeta-chain (TCR) associated protein kinase 70kDa
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-ZAP70 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-p-ZAP-70 (Tyr319) Antibody, clone 1B10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, human, monkey, mouse, rat
应用
flow cytometry
immunocytochemistry
immunohistochemistry
peptide synthesis
western blot
immunocytochemistry
immunohistochemistry
peptide synthesis
western blot
Anti-ZAP-70 Antibody, clone 2F3.2, clone 2F3.2, Upstate®, from mouse,
物种反应性
human
应用
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-ZAP-70 Antibody, clone 1D9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-p-ZAP-70 (Tyr493) Antibody, clone 1F10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Proteins
货号
说明
物种
ZAP-70 Tyrosine Kinase human, ≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells (Histidine tagged), buffered aqueous glycerol solution, ≥150 U/mg,
物种
human
ZAP-70 Protein, active, 20 µg, Active, recombinant, human, full length ZAP-70 containing a C-terminal His6 tag, for use in Kinase Assays.,
物种
human