SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
别名:
BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
物种:
Human SMARCA4 (6597), Mouse Smarca4 (20586), Rat Smarca4 (171379), dog SMARCA4 (476710), sheep SMARCA4 (101116565), domestic cat SMARCA4 (101097046), Zebrafish smarca4 (353295), chicken SMARCA4 (395932), cow SMARCA4 (414274), naked mole-rat Smarca4 (101700987)
UniProtKB ID:
基因ID:
- Human(6597) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(20586) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Rat(171379) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- dog(476710) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- sheep(101116565) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- domestic cat(101097046) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Zebrafish(353295) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- chicken(395932) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- cow(414274) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- naked mole-rat(101700987) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- domestic guinea pig(100719729) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
抗SNF2β / BRG1抗体, serum, Upstate®,
物种反应性
human, mouse, rat
应用
immunoprecipitation (IP)
western blot
western blot
抗-SMARCA4抗体，克隆20C3.2, clone 20C3.2, from mouse,
物种反应性
human, rat
应用
immunocytochemistry
western blot
western blot
Anti-BRG1 Antibody, clone 1N12, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SMARCA4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-BRG1/SMARCA4 Antibody, clone 20C3.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, rat
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
esiRNA
货号
说明
物种