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Merck
CN

PDCD6IP

programmed cell death 6 interacting protein

别名:
AIP1, ALIX, DRIP4, HP95
物种:
UniProtKB ID:
基因ID:
  • Human(10015) Summary: This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
  • Mouse(18571) programmed cell death 6 interacting protein
  • Rat(501083) programmed cell death 6 interacting protein
  • naked mole-rat(101711093) programmed cell death 6 interacting protein
  • dog(477015) programmed cell death 6 interacting protein
  • chicken(420725) programmed cell death 6 interacting protein
  • Zebrafish(406669) programmed cell death 6 interacting protein
  • sheep(101113964) programmed cell death 6 interacting protein
  • cow(533406) programmed cell death 6 interacting protein
  • Horse(100050741) programmed cell death 6 interacting protein
  • domestic cat(101095279) programmed cell death 6 interacting protein
  • domestic guinea pig(100720447) programmed cell death 6 interacting protein

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Antibodies

货号
说明
物种反应性
应用
Anti-Pdcd6Ip Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
Anti-AIP1/Alix Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
immunocytochemistry
western blot
Anti-PDCD6IP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-ALIX/PDCD6IP Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, human, monkey, mouse, porcine
应用
affinity binding assay
immunohistochemistry

western blot
Anti-ALIX, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse
应用
immunocytochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PDCD6IP,
物种
human
MISSION® esiRNA, targeting mouse Pdcd6ip,
物种
mouse