KIFAP3
kinesin-associated protein 3
FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1
Human KIFAP3 (22920), Mouse Kifap3 (16579), Rat Kifap3 (289168), naked mole-rat Kifap3 (101721676), domestic guinea pig Kifap3 (100718672), Domestic Rabbit KIFAP3 (100345771), sheep KIFAP3 (101102827), chicken KIFAP3 (424395), domestic cat KIFAP3 (101084337), Horse KIFAP3 (100059088) ...展开
- Human(22920) Summary: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Mouse(16579) kinesin-associated protein 3
- Rat(289168) kinesin-associated protein 3
- naked mole-rat(101721676) kinesin-associated protein 3
- domestic guinea pig(100718672) kinesin-associated protein 3
- Domestic Rabbit(100345771) kinesin-associated protein 3
- sheep(101102827) kinesin-associated protein 3
- chicken(424395) kinesin-associated protein 3
- domestic cat(101084337) kinesin-associated protein 3
- Horse(100059088) kinesin-associated protein 3
- dog(100685317) kinesin-associated protein 3
- cow(518402) kinesin-associated protein 3
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Antibodies
Rabbit anti-Phospho KAP-1 (S824) Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
human, mouse
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-KIFAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
human
immunohistochemistry
Anti-KIFAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
human
immunohistochemistry
Anti-KIFAP3 Antibody, clone 1S7J7, Rabbit Monoclonal, ,
human, rat
immunofluorescence
western blot
western blot