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安全信息

PLA0140

Sigma-Aldrich

Rabbit anti-Phospho KAP-1 (S824) Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

别名:

E3 SUMO-protein ligase TRIM28, KAP-1, KAP1, KRAB [Kruppel-associated box domain]-associated protein 1, KRAB-associated protein 1, KRAB-interacting protein 1, KRIP-1, PPP1R157, RING finger protein 96, RNF96, TF1B, TIF1-beta, TIF1B, Tripartite motif-containing protein 28, nuclear corepressor KAP-1, protein phosphatase 1, regulatory subunit 157, transcriptional intermediary factor 1-beta

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.43

生物来源

rabbit

质量水平

100

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

等级

Powered by Bethyl Laboratories, Inc.

种属反应性

mouse, human

技术

immunocytochemistry: 1:200-1:1,000
immunofluorescence: 1:200-1:1,000
immunohistochemistry: 1:2000-1:1,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000

登记号

NP_005753.1

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

phosphorylation (pSer824)

基因信息

human ... KIFAP3(22920)

免疫原

Immunogen was a synthetic phosphorylated peptide, which represented a portion of human KRAB-Associated Protein 1 surrounding Serine 824 according to the numbering given in entry NP_005753.1 (GeneID 10155).

外形

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他说明

KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
含少量动物源组分生物产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
5
2

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Lei Shi et al.
Nature communications, 10(1), 2588-2588 (2019-06-15)
The brain is a genomic mosaic shaped by cellular responses to genome damage. Here, we manipulate somatic genome stability by conditional Knl1 deletion from embryonic mouse brain. KNL1 mutations cause microcephaly and KNL1 mediates the spindle assembly checkpoint, a safeguard
Kasumi Kawamura et al.
Journal of radiation research, 60(3), 281-288 (2019-03-07)
The nucleolus contains multiple copies of ribosomal (r)DNA, which indicate sites of frequent replication stress and suggest the existence of a mechanism to prevent replication stress-related rDNA instability and the possibility that such a mechanism contributes to the whole genomic
Matthias Pfeifer et al.
Journal of immunology (Baltimore, Md. : 1950), 202(12), 3423-3433 (2019-05-16)
Induction of programmed DNA damage and its recognition and repair are fundamental for B cell development. The ssDNA-binding protein SSB1 has been described in human cells as essential for the recognition and repair of DNA damage. To study its relevance
Bo-Ruei Chen et al.
The Journal of cell biology, 218(7), 2113-2123 (2019-05-28)
XRCC4-like factor (XLF) is a non-homologous end joining (NHEJ) DNA double strand break repair protein. However, XLF deficiency leads to phenotypes in mice and humans that are not necessarily consistent with an isolated defect in NHEJ. Here we show that

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