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Merck
CN
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主要文件

安全信息

SAB5702585

Sigma-Aldrich

Anti-KIFAP3 Antibody, clone 1S7J7, Rabbit Monoclonal

别名:

FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

物料

colorless

克隆

1S7J7, monoclonal

表单

liquid

分子量

100 kDa

种属反应性

rat, rat, human

浓度

0.61 mg/mL

技术

immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000

颜色

colorless

同位素/亚型

IgG

免疫原序列

KFRWHNSQWLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLIASEGAISPDFFNDYHLQNGDVVGQHSFPGSLGMDGFGQPVGILGRPATAYGFRPDEPYYYGYGS

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... KIFAP3(22920)

一般描述

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

免疫原

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 675-792 of human KIFAP3 (Q92845).

应用

WB, IF/ICC

储存分类代码

10 - Combustible liquids

WGK

WGK 1

法规信息

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