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Merck
CN

CYP11B2

cytochrome P450, family 11, subfamily B, polypeptide 2

别名:
ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo
物种:
UniProtKB ID:
基因ID:
  • Human(1585) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008]
  • Mouse(13072) cytochrome P450, family 11, subfamily b, polypeptide 2
  • Rat(24294) cytochrome P450, family 11, subfamily b, polypeptide 2
  • domestic guinea pig(100379213) aldosterone synthase
  • Domestic Rabbit(100328543) cytochrome P450, family 11, subfamily B, polypeptide 2
  • cow(282423) cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2
  • dog(482071) cytochrome P450, family 11, subfamily B, polypeptide 2

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Antibodies

货号
说明
物种反应性
应用
抗-CYP11B2抗体,克隆41-17B, clone 41-17B, from mouse,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

western blot
Anti-Cyp11B2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-CYP11B2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-CYP11B2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗-细胞色素P450醛固酮合成酶抗体,克隆1G5, culture supernatant, clone 1G5, Chemicon®,
物种反应性
mouse, rat
应用
ELISA
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
酮康唑, 99.0-101.0% (EP, titration),
物种
mouse, human, rat
酮康唑, ,
物种
mouse, human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CYP11B2,
物种
human